0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
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Max Marks: 501. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
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5. Write legibly.Section 1
1. Give an account of any TWO of the following
(10)
a) Role of kidney in acid base regulation (A.
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399) (C.477)b) Principle and significance of Van Den Bergh's
reaction(A.332) (C.455)
c) Isoenzymes and their clinical significance (A.
69) (C.112)
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2. Write Short notes of (any three)(9)
a) Glycosides (A. 93) (C.17)
b) Essential fatty acid (A. 242) (C.509)
c) Allosteric enzymes (A. 66) (C.95)
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d) Radioisotopes of medical significance (A. 682)(C.717)
e) Fluid mosaic model of membrane (A. 13)
(C.650)
3. Discuss Any TWO
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(6)a) Acute intermittent porphyria (A. 328) (C.212)
b) Beer-Lambert's Law (A. 437) (C726)
c) Active and passive transport (A. 15) (C. 651)
Section 2
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4. Write Short notes on (any two)(10)
a) Steps of beta-oxidation of fay acids (A. 194)
(C.287)
b) Oxidation of pyruvate (A. 135) (C.252)
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c) Key reactions of Gluconeogenesis (A. 135)(C.258)
5. Write Short notes on (any two)
(9)
a) Immunoglobulins (A. 649) (C.186)
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b) Antioxidants (A. 429) (C.658)c) Cori cycle (A. 134) (C. 261)
d) Substrate level phosphorylation (A. 313)
(C.224)
e) Regulation of citric acid cycle (A. 308) (C.257)
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6. Give your comments with justification of AnySIX:
(6)
a) Bile salts are required for digestion of lipids.
b) Enzymes are proteins.
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c) Sucrose is called as invert sugar.d) Cyanide causes instantaneous death.
e) People with Glucose 6-phosphate deficiency are
resistant against malaria.
f) Phytanic acid cannot be oxidized by beta-
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oxidation without prior modification of beta carbonatom.
g) Acetyl CoA is a common metabolic
intermediate.
h) Lysolecithin is formed during snake bite.
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