0819E379
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
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Max Marks: 100Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Fill in the blanks:
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(6)a. SDA value for proteins is
b. Blood Urea Nitrogen = Blood Urea X
c. The jumping genes are also called
d. The guardian of the genome is
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e. In Eukaryotes the mRNA duringtranscription is synthesized by enzyme.
f. The names of two light chains of Ig are
and
2. Choose the correct option in the following
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multiple choice questions:(4)
a. Western blotting techniques is for
detection of: a) Protein b) RNA c)DNA d)
All
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b. Tumour marker used for the diagnosis andmanagement of ovarian cancer: a) TPA b)
PSA c) CA-125 d) VMA
c. Xeroderma Pigmentosum occurs due to
defect in: a) Base excision repair b)
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Double strand break repair c) Nucleotideexcision repair d) Mismatch repair
d. Monoclonal antibodies are prepared by
cloning: a) Myeloma cells b) Hybridoma
cells c) T-lymphocytes d) B-lymphocytes
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3. Clinical Case Study: A two day old baby onexamination was found to be icteric. Laboratory
findings shows serum billrubin was 12.8 mg/dL:
(15)
a. What is the probable diagnosis?
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b. What are the precursors of bilirubin and
what are different types of bilirubin?
c. Which type of bilirubin is high in this
disease?
d. What can be the enzyme defect in this
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disease?e. How is the above disease treated?
4. Write short notes on (Any five):
(10)
a. Supports of uterus
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b. Foot dropc. Ligaments of hip joint
d. Microanatomy of trachea
e. Typical Intercostal space
f. Openings in diaphragm
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Section 25. Explain briefly (Any three):
(15)
a. Thoracic duct
b. Dorsalis pedis artery
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c. Adductor canald. Portocaval anastomosis
6. Describe stomach under following headings:
(20)
a. Gross features
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b. Relationsc. Blood supply and lymphatic drainages
d. Clinical anatomy
7. Write short notes on (Any five):
(10)
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a. Microanatomy of ureterb. Medial longitudinal arch of foot
c. Right coronary artery
d. Perineal body
e. Nerve supply of urinary bladder
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f. Plantar aponeurosis8. Explain briefly (Any four):
(20)
a. Interior of right atrium
b. Bronchopulmonary segments
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c. Coeliac trunkd. Gluteus maximus muscle
e. Extensor Retinaculum of ankle