Date: 15-01-2010
0819E379
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours

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Max Marks: 50
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.

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4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
following

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(10)
a) Replication of DNA. (A. 559) (C.524)
b) Catabolism of purines &hyperuricemia

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b) Catabolism of purines &hyperuricemia
(A. 547)(C.394)

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c) Functional classification of proteins with
example. (A. 43) (C. 63)
2. Write Short notes of (any three)
(9)
a) Silent mutation (A. 591) (C.535)

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b) m-RNA & its functions (A. 570) (C. 81)
c) Post translational modifications (A. 584)
(C.561)
d) Restriction endonucleases (A. 601)
(C.579)

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e) Role of copper in the body (A. 503)
(C.416)
3. Discuss Any TWO
(6)

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a) Purine salvage pathway. (A. 546)

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(C.391)
b) Denaturation of proteins (A. 40) (C.61)
c) Pellagra (A. 470) (C.141)
Section 2
4. Write Short notes on (any two)

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(10)
a) Metabolism of tyrosine (A. 288) (C.346)
b) Urea cycle (A. 258) (C.337)
c) Functions and regulation of serum
calcium (A. 492) (C. 405)

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5. Write Short notes on (any two)
(9)
a) Transamination (A. 256) (C. 332)

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b) Vitamin E: Sources and functions (A.
460) (C.128)

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c) Hartnup's disease (A. 296) (C.654)
d) Selenium (A. 504) (C.421)
e) Second messengers. (A. 623) (C.430)
6. Give your comments with justification
of Any SIX: 35 year old pregnant woman

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from poor family came with a complaint
of weakness Breathlessness and fatigue.
On examination she was pale, her
hemoglobin was 7.0gms % & peripheral
smear showed hypochromic microcytic

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R.B.Cs.
(6)
a) What is your diagnosis?
b) What is RDA of Iron in adult female?

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c) What is RDA of Iron during pregnancy?

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d) Name two important factors which
increase iron absorption in G.I.T
e) Name protein which transports iron.
f) Name proteins which store iron in the
body

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g) How much is total iron present in the
body?
h) Name the condition where iron overload
occurs.

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