0819E379
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Time: 3 hours
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Max Marks: 501. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
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(10)a) Describe various steps in recombinant
DNA Technology and its application in
medical sciences (A. 600) (C. 579)
b) How blood calcium homeostasis is
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regulated. (A. 493) (C. 407)
c) Biologically important molecules
synthesized from phenylalanine and
tyrosine. (A. 289) (C.348)
2. Write Short notes of (any three)
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(9)a) Watson-crick model of DNA structure
(A. 556) (C.73)
b) Functions and deficiency of vitamin C
(A. 481) (C.132)
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c) Mutations (A. 591) (C.535)d) Post translational modifications (A.
584) (C.561)
e) Modified nitrogenous bases as
anticancer agents (A.546, 551)
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3. Discuss Any TWO(6)
a) Calculate the energy requirement of a
male medical student(A.518)
b) Role of liver in integrating the
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metabolism of various biomolecules (A.121) (C.382)
c) Short note on gout (A. 548) (C. 394)
Section 2
4. Write Short notes on (any two)
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(10)a) Secondary structure of proteins (A.
38) (C. 56)
b) How ammonia is detoxified in human
body (A. 258) (C.335)
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c) Briefly discuss requirement, source,factors effecting absorption and
regulation of iron absorption. (A. 498)
(C.414)
5. Write Short notes on (any two)
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(9)a) Write coenzyme form of different
water soluble vitamins in table format.
(A. 55)
b) How pyrimidines are biosynthesized
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in our body. (A.549) (C.398)c) Short note on Kwashiorkor. (A. 517)
(C.516)
d) Adenosine deaminase deficiency. (A.
549) (C.397)
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e) Maple syrup urine disease. (A. 282)(C.365)
6. Give your comments with justification
of Any SIX
(6)
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a) Deficiency of which enzyme leads tophenyketonuria.
b) Deficiency of B6 vitamin leads to
decrease hemoglobin.
c) Taking a mixed protein diet leads to
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improved body growth.d) Deficiency of copper leads to
weakening of wall of major blood vessels
e) Folic acid deficiency leads to
homocystenemia.
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f) FIGLU test. (A. 297)g) Proline is not an amino acid.
h) What is the major energy source of
brain in starvation?