0819E379
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Date: 10-01-2014
Time: 3 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
Section 1
1. Give an account of any TWO of the
following
(10)
(C.73)
b) Medical applications of Recombinant
DNA technology(A.600)(C.579)
c) Metabolic role and deficiency
2. Write Short notes of (any three)
(9)
a) Primary structure of protein (A. 36)
(C.52)
122) (C. 383)
c) t-RNA (A. 578) (C. 81)
d) Gout (A. 548) (C. 394)
e) Biologically important nucleotides
(6)
a) Specific dynamic action (A. 512)
(C.505)
b) BMR (A. 512) (C.504)
Section 2
4. Write Short notes on (any two)
(10)
a) Trace elements (A. 491) (C.405)
c) Metabolic role of sulfur containing
amino acids (A.272) (C.358)
5. Write Short notes on (any two)
(9)
b) Calcium homeostasis (A. 493) (C. 407)
c) Synthetic analogues of nucleotides used
in medicine (A.546, 551)(C.73)
d) Metabolic role of Vitamin B-6 (A. 471)
e) Inhibitors of protein biosynthesis (A.
584) (C.558)
6. Give your comments with justification of
Any SIX: A middle aged fair lady came to
surgical OPD with severe spasmodic pain in
the right upper abdomen. She jaundice
(6)
and palpable liver. Her serum Total Bilirubin
was 9 mg% (normal 0.2-1 mg%) & Alkaline
13 KAU/dl). Prothrombin time was grossly
elevated. The case was diagnosed as
"Obstructive jaundice due to gall stone". The
surgeon prescribed Vit K (Injectable form) prior
a) What are the functions of Vitamin K?
b) How Vit K is related with prothrombin
time?
c) Correlate her alkaline phosphatase level
d) What is the name of injectable form of
Vit K?
e) How prolong antibiotic therapy causes
Vit K deficiency?
Hypervitaminosis of Vit K?
g) How the drug Warfarin has an
interaction with Vit K?
h) What is hemorrhagic disease of new
First Year MBBS Examination
I MBBS Biochemistry Paper 2
Date: 10-01-2014
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 501. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
--- Content provided by FirstRanker.com ---
5. Write legibly.Section 1
1. Give an account of any TWO of the
following
(10)
--- Content provided by FirstRanker.com ---
a) Structure and functions of DNA (A. 556)(C.73)
b) Medical applications of Recombinant
DNA technology(A.600)(C.579)
c) Metabolic role and deficiency
--- Content provided by FirstRanker.com ---
manifestations of Vit.A(A.454) (C.119)2. Write Short notes of (any three)
(9)
a) Primary structure of protein (A. 36)
(C.52)
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b) Metabolic changes in starvation (A.122) (C. 383)
c) t-RNA (A. 578) (C. 81)
d) Gout (A. 548) (C. 394)
e) Biologically important nucleotides
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3. Discuss Any TWO(6)
a) Specific dynamic action (A. 512)
(C.505)
b) BMR (A. 512) (C.504)
--- Content provided by FirstRanker.com ---
c) Dietary fibres (A. 514) (C.508)Section 2
4. Write Short notes on (any two)
(10)
a) Trace elements (A. 491) (C.405)
--- Content provided by FirstRanker.com ---
b) Transdeamination (A. 256) (C.334)c) Metabolic role of sulfur containing
amino acids (A.272) (C.358)
5. Write Short notes on (any two)
(9)
--- Content provided by FirstRanker.com ---
a) Rickets (A. 459) (C.127,408)b) Calcium homeostasis (A. 493) (C. 407)
c) Synthetic analogues of nucleotides used
in medicine (A.546, 551)(C.73)
d) Metabolic role of Vitamin B-6 (A. 471)
--- Content provided by FirstRanker.com ---
(C.134)e) Inhibitors of protein biosynthesis (A.
584) (C.558)
6. Give your comments with justification of
Any SIX: A middle aged fair lady came to
--- Content provided by FirstRanker.com ---
surgical OPD with severe spasmodic pain in
the right upper abdomen. She jaundice
(6)
and palpable liver. Her serum Total Bilirubin
was 9 mg% (normal 0.2-1 mg%) & Alkaline
--- Content provided by FirstRanker.com ---
phosphatase level was 150 KAU/dl (Normal 3-13 KAU/dl). Prothrombin time was grossly
elevated. The case was diagnosed as
"Obstructive jaundice due to gall stone". The
surgeon prescribed Vit K (Injectable form) prior
--- Content provided by FirstRanker.com ---
to surgery of removal of gall bladder.a) What are the functions of Vitamin K?
b) How Vit K is related with prothrombin
time?
c) Correlate her alkaline phosphatase level
--- Content provided by FirstRanker.com ---
with the cause of jaundice.d) What is the name of injectable form of
Vit K?
e) How prolong antibiotic therapy causes
Vit K deficiency?
--- Content provided by FirstRanker.com ---
f) What are the sign symptoms ofHypervitaminosis of Vit K?
g) How the drug Warfarin has an
interaction with Vit K?
h) What is hemorrhagic disease of new
--- Content provided by FirstRanker.com ---
born?