Download Gujarat University MBBS 2nd Year 0122 E492 Pathology Paper I Jan 2022 Question Paper

Date: 20-01-2022
0122 E492
Second Year MBBS Examination
II MBBS Pathology Paper 1
Time: 3 hours

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Max Marks: 100
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.

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4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Structured Long Question (Any 1 out
of 2)

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(10)
a) Define thrombus. Describe
thrombogenesis. Add a note on fate of
thrombus
(3+4+3=10 Marks)

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b) Define shock, mention types and discuss
the etiopathogenesis of septic shock

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2. Case based
(2+3+5=10 Marks)
scenario/Applied short notes (Any 2 out

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of 3)
(12)
a) A 50 years male presented with chest pain
one day with tachycardia, hypotension and
shock Laboratory investigations are as

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follows:Hb:14.5 gms%, TLC: 12,500
cells/cu mm,DLC:N-76%, L-21% E-2% M-
4%,B-0% ESR: 30
mm/hr,CPK:250III/L,CPK-MB:100 IU/L,
ASAT:100 IU/L, Troponin I: Present. a)

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What is your likely diagnosis? b)Write
pathogenesis and complications of the same.
b) A 8-year old boy was admitted with
history of puffiness of face & passing of red
coloured urine following upper respiratory

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tract infection 2 weeks earlier. Urine
examination showed moderate proteinuria
and hematuria. a) What is your likely
diagnosis and the organ affected? b)
Describe the etiopathogenesis of the

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condition c) List the investigations that you

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would do to confirm diagnosis.
c) Brown atrophy of heart.
3. Write short notes (Any 3 out of 4) (18)
a) Phagocytosis

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b) Metastasis
c) Role of Peripheral smear and bone
marrow and its importance in diagnosing
megaloblastic anaemia
d) What is AETCOM? Discuss the role of

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health care worker, working in a health care
team, in a malaria outbreak.
4. Answer only in 2-3 sentences (Any 5
out of 6)
(10)

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a) Define neoplasia. Write two differences
between benign and malignant tumors,
giving examples.

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b) Factors influencing wound healing.
c) Difference between lepromatous and

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tuberculoid leprosy.
d) Types of giant cells.
e) Philadelphia chromosome.
f) Vitamin A deficiency diseases.
Section 2

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5. Structured long essay Question (Any 1
out of 2)
(10)
a) Define anaemia. Give the etiological
classification of anaemias. Describe the

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peripheral smear and bone marrow picture of
Iron deficiency anemia
(2+3+5)
b) Define and classify leukaemias. Discuss
peripheral blood smear, bone marrow and

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biochemical findings in Chronic myeloid
leukaemia.
(2+3+5)

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6. Case based scenario/Applied short
Notes (Any 2 out of 3)

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(12)
a) What is Bombay blood group? Discuss in
brief its significance.
b) A male patient aged 12 years old,
presented with fever and petechial

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haemorrhages Laboratory
investigations:HB-8.5 gms%, TLC-12,500
cell/cu mm, Platelet count- 50,000
cells/cumm, Bleeding time-12 minutes,
Clotting time-6 minutes. Bone Marrow

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aspiration-Megakaryocytic hyperplasia with
agranular megakaryocytes.a) What is your
likely diagnosis? b) What is the
etiopathogenesis and complications of the
disease?

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c) Discuss the hazards of blood transfusion
and enumerate the investigations in a case of
transfusion reaction.
7. Write short notes (Any 3 out of 4) (18)

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a) Virchow's node.

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b) Urinary casts.
c) Mitsuda reaction.
d) Special stains to demonstrate Amyloid.
8. Answer only in 2-3 sentences (Any 5
out of 6)

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(10)
a) Causes of fatty liver.
b) Name two sexually transmitted diseases.
c) Two examples of metaplasia.
d) Barr body.

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e) Name two cancers caused by viruses.
f) Causes of edema.

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