Date: 04-01-2013
0113 E015
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
a) The rationale of mifepristone and
(10)
misoprostol in medical termination of
pregnancy. (A. 320, . 962)
b) Enumerate first line of antitubercular
drugs and comment on their use in different
regimens employed in the treatment of this
disease. (A. 765, B. 739)
c) Enumerate and briefly comment on the
incretin-mimetic and insulin-sensitizers in
diabetes mellitus. (A. 273, . 899)
2. Write Short notes of (any three)
a) Drugs for osteoporosis (A. 314, 337,(12)
b) Pharmacological basis of use of folic
acid in pregnancy and certain cases of
coronary heart disease. (A. 610, B. 507)
c) Drugs for enteric fever (A. 712, . 696)
778)
3. Discuss Any Three
a) Mechanism of action and
(12)
837, B. 784)
b) Mechanism of action and uses of
different classes of antiemetic drugs (A.
662, B. 589)
anticancer drugs (A. 862, . 820)
d) Mechanism and limitation lodide salt as
anrithyroid agent (A. 254, . 868)
4. Write Answer to the point in two or
a) Write mechanism of Gray-baby
(6)
syndrome seen in neonates on
chloramphenicol use. (A. 741, . 694)
synthesis inhibitor do not show cross-
resistance to other Antibiotics which act via
inhibition of bacterial protein synthesis?
(A. 758, B. 671)
perioperative prophylaxis. (A. 702)
d) Pharmacological basis of use of
aromatase inhibitors in locally advanced
breast cancer. (A.314,8.826)
of precocious puberty in both boys and
girls. (A. 242, B.928)
f) Pharmacological basis of use of
desmopressin in a variety of hemorrhagic
g) How renal toxicity of cisplatin is
prevented by amifostine? (A. 876, . 829)
h) Write mechanism of action of acyclovir
as anti-herpes drug. (A. 799, . 798)
0113 E015
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
--- Content provided by FirstRanker.com ---
Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
--- Content provided by FirstRanker.com ---
section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
--- Content provided by FirstRanker.com ---
followinga) The rationale of mifepristone and
(10)
misoprostol in medical termination of
pregnancy. (A. 320, . 962)
--- Content provided by FirstRanker.com ---
b) Enumerate first line of antitubercular
drugs and comment on their use in different
regimens employed in the treatment of this
disease. (A. 765, B. 739)
c) Enumerate and briefly comment on the
--- Content provided by FirstRanker.com ---
status on the use of drugs belonging toincretin-mimetic and insulin-sensitizers in
diabetes mellitus. (A. 273, . 899)
2. Write Short notes of (any three)
a) Drugs for osteoporosis (A. 314, 337,(12)
--- Content provided by FirstRanker.com ---
340, 343, . 940)b) Pharmacological basis of use of folic
acid in pregnancy and certain cases of
coronary heart disease. (A. 610, B. 507)
c) Drugs for enteric fever (A. 712, . 696)
--- Content provided by FirstRanker.com ---
d) Drugs for cerebral malaria (A. 826, .778)
3. Discuss Any Three
a) Mechanism of action and
(12)
--- Content provided by FirstRanker.com ---
pharmacological uses of Metronidazole (A.837, B. 784)
b) Mechanism of action and uses of
different classes of antiemetic drugs (A.
662, B. 589)
--- Content provided by FirstRanker.com ---
c) Mechanism and uses of antimetaboliteanticancer drugs (A. 862, . 820)
d) Mechanism and limitation lodide salt as
anrithyroid agent (A. 254, . 868)
4. Write Answer to the point in two or
--- Content provided by FirstRanker.com ---
three sentences: (any six)a) Write mechanism of Gray-baby
(6)
syndrome seen in neonates on
chloramphenicol use. (A. 741, . 694)
--- Content provided by FirstRanker.com ---
b) Explain why linezolid as proteinsynthesis inhibitor do not show cross-
resistance to other Antibiotics which act via
inhibition of bacterial protein synthesis?
(A. 758, B. 671)
--- Content provided by FirstRanker.com ---
c) Write antibiotic of choice forperioperative prophylaxis. (A. 702)
d) Pharmacological basis of use of
aromatase inhibitors in locally advanced
breast cancer. (A.314,8.826)
--- Content provided by FirstRanker.com ---
e) GnRH agonists are used in the treatmentof precocious puberty in both boys and
girls. (A. 242, B.928)
f) Pharmacological basis of use of
desmopressin in a variety of hemorrhagic
--- Content provided by FirstRanker.com ---
conditions. (A. 597, B.488)g) How renal toxicity of cisplatin is
prevented by amifostine? (A. 876, . 829)
h) Write mechanism of action of acyclovir
as anti-herpes drug. (A. 799, . 798)
--- Content provided by FirstRanker.com ---