0119E519
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Write briefly (any two)
(10)
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a) Classify anti-depressant drugs. Writemechanism of action, pharmacological
action of fluoxetine. Therapeutic uses &
adverse effects of fluoxetine.
b) Classify anti-anginal drugs. Write
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mechanism of action & pharmacologicalaction of atenolol. Therapeutic uses &
adverse effects of atenolol.
c) Classify anti-cholinergic drugs. Write
mechanism of action & pharmacological
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action of atropine. Therapeutic uses &adverse effects of atropine.
2. Write briefly (any three)
(12)
a) Clinical uses of a-blockers.
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b) Lifesaving uses of adrenalinec) Drug Therapy for chronic simple
glaucoma(A. 152, . 1030)
d) Uses & adverse effects of H1 anti
histaminic
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3. Write briefly (any three)(12)
a) Phramacotherapy of myasthenia
gravis(A. 109, . 287)
b) Pharmacotherapy of status epileptics
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c) Dopamine(A. 134, . 248)d) Factors affecting bioavailability(A. 16,
B. 11, 12)
4. Answer in one or two sentences (any
six):
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(6)a) Pharmacological basis for the use of
frusemide in congestive cardiac failure
(A.579, 8.556)
b) Pharmacological basis for the use of
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ACE inhibitors in hypertensionc) Pharmacological basis for the use of
steroids in bronchial asthma.
d) Pharmacological basis for the use of
olanzapine in psychiatric illness
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e) Pharmacological basis for the use ofamantadine in Parkinson's disease
f) Pharmacological basis for the use of
streptokinase in myocardial infarction(A.
627, . 406)
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g) Pharmacological basis for the use ofdimercaprol in mercury poisoning
h) Half-life of drugs.