0712 E014
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 401. Answer to the points.
2. Figure to the right indicates
marks.
3. Use separate answer books for
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each section.4. Draw diagrams wherever
necessary.
5. Write legibly.
Section 1
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1. Give an account of any TWO of thefollowing
(10)
a) Describe the methods of prolonging
the duration of action of drug with
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examples. (A. 34, B. 24)b) Explain pharmacological basis of
levodopa in Parkinsonism and explain its
advantages & disadvantages. (A. 426, .
231)
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c) Write mechanism of action,pharmacological action, clinical uses and
adverse effect of Lignocaine. (A. 361, .
241)
2. Write Short notes of (any three)
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(12)a) Write mechanism of action of digitalis.
Write management of its toxicity. (A. 514,
B. 445)
b) Therapeutic uses of calcium channel
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blockers. (A. 550, . 400)c) Write note on various heparin
preparation and analogues (A. 667, B.
473)
d) Add note on Halothene (A. 379, . 98)
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3. Discuss Any Three
(12)
a) Write two beneficial and two harmful
drug interaction. (A. 15, B. 63)
b) Write mechanism of action and clinical
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uses of carbolic anhydrase inhibitors (A.586, . 551)
c) Write clinical uses where propranolol
is preferred with justification (A. 149, B.
276)
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d) Explain the cardiovascular effects ofadrenaline, noradrenaline and
isoprenaline (A. 130, B. 258)
4. Write Answer to the point in two or
three sentences: (any six)
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(6)a) Give any two examples in which the
drug act through its physical property
with explanation. (A.37,B. 29)
b) Define cumulative toxicity. Give two
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examples. (A. 69, B. 40)
c) Write the basis of edrophonium test in
myasthenia gravis. (A. 110, B. 286)/ Give
reasons: Edrophonium is preferred over
neostigmine for diagnosis of myasthenia
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gravis.d) Write two drugs used in acute gout
with different mechanism of action. (A.
213, B. 286)
e) Define disulfiram like reaction with
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alcohol. (A. 394, . 90)f) Write difference between nifidepine and
amlodepine. (A. 549, B. 399)
g) Write prostaglandin analogue used in
glaucoma. (A. 154, B. 1029)
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h) Write drugs used in acute asthma. (A.222, B. 356)
Document Outline
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