0713 E014
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
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following(10)
a) 'p' drug concept (B. 54)
b) Non-epileptic uses of anti-epileptic
drugs explaining rationale for each of the
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use.c) Mechanism of action pharmacological
effects,adverse reactions & therapeutic
uses of enalapril (A.502,8.421)
2. Write Short notes of (any three)
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(12)a) Clinical significance of enzyme
induction with suitable example.
(A.26,B.19)/ what is enzyme induction?
Name the drugs causing it and its clinical
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significance.b) Uses of H1 antihistaminics. (A. 166,
. 320, 324)
c) Pharmacological basis for uses of
prostaglandin analogues in glaucoma (A.
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154, B. 1030)d) Therapy of scorpion bite (B. 1097)
3. Discuss Three
(12)
a) Pharmacological basis for uses of
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inhalational steroids in bronchial asthmaand their adverse effects. (A. 230, B. 361)
b) Mechanism of action, therapeutic uses
and adverse reactions of Neostigmine. (A.
105, . 284)
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c) Compare and contrast nifedipine andverapamil. (A. 548, B. 399)
d) Selective COX-2 inhibitors. (A. 205,
. 175)
4. Write Answer to the point in two or
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three sentences; (any six)(6)
a) Why aluminium containing antacids
are combined with magnesium containing
antacids? (A. 655, B. 619)
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b) Give rationale for uses of flavoxate incystitis. (A. 118, 297)
c) What are the advantages of neurolept
analgesia? (B. 104)
d) Why leukotriene modifiers are not
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preferred as rescue drugs in acute attackof asthma? (A.228, 8.360)
e) What is the rationale for use of nicotine
transdermal patches in chronic smokers?
(A. 122, B. 305)
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f) Explain is the pharmacological basisfor use furosemide for pulmonary edema.
What is the dose and route of
administration? (A. 581, . 455)
g) Why salt depletion should be watched
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for & prevented in patients taking lithiumcarbonate? (A.448,8.213)
h) Name an antihypertensive of choice in
pregnancy. State the reasons for the same.
(A. 572, . 433)
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