Date: 01-07-2014
0714 E015
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
Section 1
1.Give an account of any TWO of the
following
(10)
affecting drug metabolism with their
clinical significance.
b) Enumerate antiepileptic agents.
Describe mechanism of action &
417, .131)
c) Describe therapeutic uses and adverse
effects of aspirin.
2.Write Short notes of (any three)
a) Describe briefly with examples; (1)
Therapeutic window phenomena
(2)'Orphan'drugs
b) Write short notes on 'Atropine
c) Classify agents used for Parkinsonism
on the basis of their mechanism of action.
d) Compare and contrast; Ether and
Halothene
(12)
a) Describe briefly mechanism of action
and therapeutic uses of nitrates
b) Write short notes on 'Antitussive
c) Describe briefly pharmacological
actions and therapeutic uses of Digoxin
d) Classify diuretics. Explain clinical
limitations to use of thiazides.
4.Write Answer to the point in two or
three sentences; (any six)
(6)
a) Give reasons; Pyridostigmine is
preferred to Neostigmine for myasthenia
b) Mention merits of combining
adrenaline with local anesthetic agents.
(A. 363, B. 241)
c) Justify:Ipratropium bromide is not used
asthma.
d) Enlist therapeutic uses of ACE
inhibitors. (A. 501, . 422)
e) Explain pharmacological basis for the
f) Justify, Thiopental sodium is an ultra
short acting barbiturate.
g) Explain pharmacological basis for the
use of atorvastatin in
h) Give two examples of (a) inhaled
steroids (b) mucolytic agents
0714 E015
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
--- Content provided by FirstRanker.com ---
Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.
--- Content provided by FirstRanker.com ---
5. Write legibly.Section 1
1.Give an account of any TWO of the
following
(10)
--- Content provided by FirstRanker.com ---
a) Define prodrug. Describe factorsaffecting drug metabolism with their
clinical significance.
b) Enumerate antiepileptic agents.
Describe mechanism of action &
--- Content provided by FirstRanker.com ---
therapeutic uses of sodium valproate. (A.417, .131)
c) Describe therapeutic uses and adverse
effects of aspirin.
2.Write Short notes of (any three)
--- Content provided by FirstRanker.com ---
(12)a) Describe briefly with examples; (1)
Therapeutic window phenomena
(2)'Orphan'drugs
b) Write short notes on 'Atropine
--- Content provided by FirstRanker.com ---
substitutesc) Classify agents used for Parkinsonism
on the basis of their mechanism of action.
d) Compare and contrast; Ether and
Halothene
--- Content provided by FirstRanker.com ---
3.Discuss Any Three(12)
a) Describe briefly mechanism of action
and therapeutic uses of nitrates
b) Write short notes on 'Antitussive
--- Content provided by FirstRanker.com ---
agents'c) Describe briefly pharmacological
actions and therapeutic uses of Digoxin
d) Classify diuretics. Explain clinical
limitations to use of thiazides.
--- Content provided by FirstRanker.com ---
4.Write Answer to the point in two or
three sentences; (any six)
(6)
a) Give reasons; Pyridostigmine is
preferred to Neostigmine for myasthenia
--- Content provided by FirstRanker.com ---
gravis?b) Mention merits of combining
adrenaline with local anesthetic agents.
(A. 363, B. 241)
c) Justify:Ipratropium bromide is not used
--- Content provided by FirstRanker.com ---
as a single agent for acute attack ofasthma.
d) Enlist therapeutic uses of ACE
inhibitors. (A. 501, . 422)
e) Explain pharmacological basis for the
--- Content provided by FirstRanker.com ---
use of fomepizole in methanol poisoning.f) Justify, Thiopental sodium is an ultra
short acting barbiturate.
g) Explain pharmacological basis for the
use of atorvastatin in
--- Content provided by FirstRanker.com ---
hypercholesterolaemia. (A.635, 637)h) Give two examples of (a) inhaled
steroids (b) mucolytic agents