0717 E092
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write briefly (any two)
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(10)a) Classify antimalarial drugs. Describe
artemisinin based combination therapy
(ACT) in acute uncomplicated falciparum
malaria. (A. 833, . 780)
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b) Classify oral hypoglycemic drugs.
Describe the mechanism of action, side
effects and advantages of metformin in type
2 diabetes mellitus.(B. 897)
c) Classify drugs for the treatment of peptic
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ulcer. Describe the mechanism of action,adverse effects and clinical status of
pantoprazole. (A. 657, B. 624)
2. Write briefly (any three)
(12)
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a) Metronidazole (A. 837, B. 784)b) Toxicity of cytotoxic drugs (A.858)
c) Desferrioxomine (A.907)
d) Raloxifine (A.314)
3. Write briefly (any three)
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(12)a) Drugs used for acne vulgaris
b) Loperamide (A. 687, B. 598)
c) Meropenem (A. 731)
d) Folic acid (A. 610, . 507)
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4. Answer in one or two sentences (anysix):
(6)
a) Pharmacological basis for the use of
streptokinase in acute myocardial infarction
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b) Pharmacological basis for the use ofbromocriptine in hyperprolactinemia
c) Pharmacological basis for the use of
terbinafine as topical antifungal (A. 796, B.
699)
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d) Pharmacological basis for the use ofheparin in venous thrombosis (A. 619, .
475)
e) Pharmacological basis for the use of
carbenicillin and gentamycin
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f) Pharmacological basis for the combine useof lamivudine, zidovudine and efavivenz in
AIDS
g) Therapeutic status of glucocorticoids as
an antiallergic
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h) Therapeutic status of clofazimine inleprosy