0801 E13
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the following
(10)
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a) Write in brief regarding the drugs used intreatment of peptic ulcer and management of
H.pylori infection. (A. 657, . 624)
b) Discuss in detail the drugs used in the
treatment of leprosy and mention the various
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regimens. Add a note on lepra reaction./ Classifydrugs used in treatment of leprosy. Discuss drug
treatment of multibacillary leprosy and lepra
reaction.
c) Classify antithyroid agents. Explain the
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mechanism of action, adverse effects,precautions& therapeutic uses of iodides and radio-active
iodine.
2. Write Short notes of (any three)
(12)
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a) Methotrexate (A. 862, B. 821)b) Therapeutic uses of metronidazole/
Metronidazole (A. 837, B. 784)
c) Allopurinol (A. 216, . 1036)
d) Metformin
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3. Discuss Any Three(12)
a) Adverse effects of glucocorticoids
b) Low molecular weight heparin (A. 619, B.
475)
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c) Vitamin A
d) Clomiphene citrate
4. Write Answer to the point in two or three
sentences; (any six)
(6)
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a) Rationale of using oxytocin and notergometrine for induction of labour
b) Why tetracyclines are contraindicated in
pregnant women and children.
c) Rifampicin, when given reduces the efficacy of
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oral contraceptives-give reason. (A.767)d) Rationale of giving chloroquine and
primaquine in acute vivax malaria.
e) Unlike other tetracyclines, doxycycline can be
safely used in patients with renal failure.
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f) Why pyridoxine is administered along withisoniazid in the treatment of tuberculosis?
g) Why ciprofloxacin is contraindicated in
children under 18 years of age?(A. 711, B. 648)
h) Treatment of megaloblastic anemia.
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