1213 E004
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
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4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the
following (10)
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a) Describe bioavailability. Discuss thefactor affecting same. (A. 16, . 11,12)
b) Describe therapeutic uses, adverse
effects and contraindications of
propranolol.(A.146,149,8.275-277)
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c) Describe mechanism of action,therapeutic uses & adverse effects of
diazepam. (A.402,405,407,8.109-111)
2. Write Short notes of (any three) (12)
a) Therapeutic drug monitoring (A.34,
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B.24)b) Explain pharmacological basis for
the use of adrenaline in anaphylactic
shock (A.87, 8.318)
c) Describe mechanism of action and
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adverse effects of phenytoin sodium (A.413, . 127)
d) Second generation (Newer)
Antihistaminics (A. 166, . 320, 324)
3. Discuss Any Three (12)
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a) Mucolytic agents (A. 219, B. 352)b) Therapeutic uses of aspirin (A. 198,
. 169)
c) High-ceiling diuretics (A. 579, B. 556)
d) Selective serotonin reuptake
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inhibitors as antidepressant agents (A.460, . 208)
4. Write Answer to the point in two or
three sentences; (any six) (6)
a) Why Neostigmine is preferred for use
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in myasthenia gravis? (A. 109, B. 285)b) Why should not Vitamin B complex
supplements be prescribed with
Levodopa monotherapy in
Parkinsonism? (A. 429, B. 228)
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c) Why is morphine contraindicated inhead injury? (A. 474, . 152)
d) Compare and contrast dopamine and
dobutamine. (A. 134, B. 264)
e) How is pilocarpine is useful in wide
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angle Glaucoma? (A. 155, . 1028)f) Explain why disulfiram is used in
chronic alcohol addiction? (A.
394,B.90)
g) Explain the phenomenon of
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redistribution using a suitable example.(A. 18,8.102)
h) Explain the role of glycopyrrolate as
a pre-anesthetic medication.
(A.386,8.106)
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