0118 E047
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write briefly (any two)
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(10)a) Factors affecting bioavailability of
drugs. (A. 16, . 11, 12)
b) Classify skeletal muscle relaxants.
Describe mechanism of action, clinical
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users and adverse effects of any of them.c) Classify sedative hypnotics. Describe
the mechanism of action, clinical uses and
adverse of benzodiazepines
2. Write briefly (any three)
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(12)a) Microsomal enzyme induction(A. 26, B.
30)
b) Inhalational corticosteroids
c) Drugs used for open angle glaucoma
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d) Drugs for controlling hypertension inpregnancy
3. Write briefly (any three)
(12)
a) Intravenous anesthetics
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b) Pharmacotherapy of Alcoholwithdrawal
c) Adverse effects of loop diuretics
d) Half-life of drugs
4. Answer in one or two sentences (any
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six):(6)
a) Pharmacological basis for use of beta
blockers in heart failure
b) Anticholinergic drug usage
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inneurodegenerative diseases
c) Pharmacological basis for use of oral
anticoagulants in preventing deep vein
thrombosis.
d) Clinical uses of prostaglandin
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analoguese) Advantages and disadvantages of fixed
dose combination of drugs
f) Disease modifying drugs in Rheumatoid
arthritis
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g) Zero order elimination kineticsh) Oral iron chelating agents