0717 E066
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write briefly (any two)
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(10)a) Classify sympathomimetic drugs.
Describe pharmacological actions,
clinical uses and adverse effects of
epinephrine. (A.129, 130)
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b) Classify drugs for migraine.Describe pharmacological actions,
therapeutic uses and adverse effects of
sumatriptan. (A. 176,178 . 333)
c) Classify opioid analgesics. Describe
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pharmacological actions of morphineon central nervous system and smooth
muscles with their clinical implications.
(A. 483, B. 151)
2. Write briefly (any three)
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(12)a) Compare and contrast d-tubocurarine
and succinylcholine(A. 353, . 312)
b) Atypical antipsychotics (A. 441, B.
195)
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c) Drug antagonism and its clinical
relevance(A. 57, . 38)
d) Clinical uses of alpha blockers(A.
150, B. 277)
3. Write briefly (any three)
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(12)a) Uses and techniques of local
anesthesia(A. 363, . 241)
b) Rivastigmine (A.489)
c) Clinically useful prostaglandin
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analogues (A. 189, . 343)d) Compare and contrast
hydrochlorthiazide and frusemide(A.
579, B. 556)
4. Answer in one or two sentences (any
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six):(6)
a) Pharmacological basis for the use of
aminophylline in bronchial asthma
b) Pharmacological basis for the use of
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benzhexol in drug inducedparkinsonism
c) Pharmacological basis for the use of
pralidoxime in organophosphorous
poisoning(A. 110, B. 289)
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d) Pharmacological basis for the use ofadenosine in treatment of paroxysmal
supraventricular tachycardia.
e) Pharmacological basis for the use of
dobutamine in cardiogenic shock
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f) Pharmacological basis for the use ofN-acetylcystine in acute paracetamol
toxicity in children.
g) Pharmacological basis for the use of
edrophonim in diagnosing myasthenia
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gravis.h) Pharmacological basis for the use of
disulphiram in chronic alcoholism