Download Gujarat University MBBS 2nd Year E111 Pharmacology Paper I Apr 2022 Question Paper

Date: 27-04-2022
0422 E111
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 3 hours

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Max Marks: 100
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each section.
4. Draw diagrams wherever necessary.

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5. Write legibly.
Section 1
1. Answer any one of the following
a)
(10)

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Enumerate the drugs used for treating
hypertension with suitable examples.
Write the mechanism of action of
Angiotensin Converting Enzyme
inhibitors with their advantages and

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disadvantages.
(5+3+2=10)
b)
Enumerate the drugs used for the

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treatment of Parkinson's Disease.

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Write the mechanism of action of
dopamine. What are the advantages
and disadvantages of levodopa and
carbidopa combination.
(5+3+2=10)

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2. Answer any two of the following:
a)
(12)
An adult male aged 42 years have
come to the emergency with

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unconsciousness frothing from mouth.
On physical and laboratory
investigations he is confirmed to be a
case of organop'nosphorus poisoning.
Describe che management of this

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pacienc and the rationale of
prescribing these drugs for this
patient.
b)
A lady presented with bronchospasm,

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low blood pressure, sweating, feeble
pulse after consuming seafood. On
examination she is diagnosed to be a
case of anaphylactic shock. Describe

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the drug management of this patient.

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Mention the rational use and mode of
administration of these drugs.
c)
A young boy aged 19 years was
brought to casualty with history of

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loss of consciousness & convulsions.
He is diagnosed to be suffering from
generalised tonic-clonic seizure.
Enumerate the group of anti-epileptic
drugs with suitable examples. Write

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the Adverse Drug Reactions of
phenytoin. Why istherapeutic drug
monitoring necessary for these drugs.
3. Write short note on any three of
the following:

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a)
(18)
Drug tolerance
b)
Bioavailability of drugs

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c)
Biocransibrmation of drugs

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d)
Drug receptors
4. Answer any five of the following

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briefly:
a)
(10)
What are Pro-drugs. Give suitable
examples.

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b)
How are iatrogenic diseases caused?
c)
What is the importance of Ethics in
clinical practice?

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d)
Mention H-I blockers with their clinical
uses.
e)
What is penicillamine? Mention its

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clinical use.
f)
Write the names and indications of Z-
drugs.

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Section 2

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5. Answer any one of the following
a)
(10)
Enumerate the drugs used for treating
Rheumatoid Arthritis with suitable

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examples. Write the mechanism of
action of Disease Modifying Anti
Rheumatoid Drugs with their common
adverse drug reactions.
(5+3+2=10)

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b)
Enumerate the drugs used in
Schizophrenia, Write the advantages
of atypical anti-psychotics with their
common adverse drug reactions.

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(5+3+2=10)
6. Answer any two or the
following:
a)
(12)

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A 27 year old primigravida during her
Is1 trimester antenatal check-up is
found to be suffering from anemia
with ankle edema. Write the
management for this patient. What are

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the common adverse drug reactions of
oral iron therapy?
b)
A 60 year old smoker driver suffers
from severe left sided chest pain. He

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was rushed by his family members to
emergency services where he is
diagnosed to be a case of acute
myocardial infarction. How would you
manage this patient? Mention the

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rationale of use and their suitable
route of administration of these drugs.
c)
A 55 year old lady visits eye OPD
with pain and diminished vision of the

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left eye since last 2 days. Her
intraocular pressure'is raised on
examination, write the drugs used in
glaucoma. Write different uses of
Acetazolamide

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7. Write short note on any three of
the following:
a)
(18)

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Use of statins with suitable examples.

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b)
Nasai decongestants commonly
employed.
c)
Nitrates and their uses

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d)
Selective Serotonin Reuptake Inhibitors
and their uses.
8. Answer any five of the following
briefly:

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a)
(10)
Mention the drug used in Paracetamol
poisoning.
b)

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Write the pharmacological actions of
aspirin with doses
c)
Write the uses of Low Molecular
Weight Heparin.

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d)

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Uses of Adrenaline with lignocaine as
local anesthetic.
e)
Name the Potassjum sparing diuretics

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and their indications
f)
Mechanism of action of
Benzodiazepines with their uses

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