079 E252
Second Year MBBS Examination
II MBBS Pharmacology Paper 2
Time: 2 hours
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Max Marks: 40Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
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section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write briefly (any two)
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(10)a) Classify oral hypoglycaemic drugs. Write
mechanism of action pharmacological actions
therapeutic uses and adverse effects of Metformin.
b) Classify antitubercular drugs. Write mechanism
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of action, pharmacological actions therapeutic uses
and adverse effects of Rifampin
c) Classify fluoroquinolones. Write mechanism of
action, pharmacological actions therapeutic uses
and adverse effects of ofloxacin
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2. Write briefly (any three)(12)
a) New insulins
b) Antiemetic drugs(A. 662, B. 590)
c) Aminoglycosides(A. 745, B. 675)
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d) Biphosphonates3. Write briefly (any three)
(12)
a) SERM (selective estrogen receptor modulators)
(A. 313, . 939)
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b) Anabolic steroids(A. 300, B. 993)c) Beta lactamase inhibitors
d) Newer antimalarial drugs(A. 833, . 780)
4. Answer in one or two sentences (any six): Give
pharmacological basis for the use of:
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(6)a) Geftriaxone in the typhoid fever
b) Metronidazole in the anaerobic infection(A.
837, B. 784)
c) Prokinetic drugs in the GERD (gastric-
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esophageal reflux disease)d) Slidenafil in erectile dysfunction
e) Oxytocin in PPh (post-partum haemorrhage)
f) Mifepristone as emergency contraceptive
g) Corticosteroid in thyroid storm
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h) Cilastatin along with Imipenem