Date: 02-01-2013
0113 E007
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
a) Relevance of pH in drug absorption
(A. 11, B. 13)
b) Pharmacological basis of different
classes of diuretics for various
c) Mechanism of action,
pharmacological effects, clinical uses
and adverse reactions of atropine
(A.113, B. 292)
(12)
a) Mechanism of action and basis
of use of aspirin and clopidogral in
coronary heart disease. (A.629,B. 471)
alpha in rheumatoid arthritis (A. 212,
B. 1041)
c) Therapeutic uses of cholinesterase
inhibitors (A. 108, B. 283)
inhalational glucocorticoids and
salbutamol in bronchial asthma. (A.
230, B. 361)
3. Discuss Any Three
a) Mechanism of action, therapeutic
uses and adverse effects of
benzodiazepines (A. 402, 405, B. 109)
b) Mechanism of action of synergistic
treatment of dyslipidemia. (A. 636, B.
582)
c) Pharmacological basis of uses and
side effects of ACE- Inhibitors and
421)
d) Pharmacological basis of use and
dose and duration dependent adverse
effects of phenytoin(A.413,B. 127)
three sentences: (any six)
(6)
a) Why timolol but not propranolol is
used in glaucoma? (A. 153, B. 1030)
response (exaggerated response to
first dose)? (A. 142, B. 417)
c) Explain how clonidine controls
diarrhoea and tinismus of diabetic GIT
d) How thiopentone sodium in IV bolus
dose acts as an ultra-short acting
general anesthetic? (A.381,B.102)/
Give reasons: Thiopental is preferred
G.A.
e) Explain why sodium nitroprusside is
contraindicated in patients with renal
impairment? (A. 567, 419)
f) State the main uses of dicyclomine
and propantheline. (A. 117, B. 297)
g) Why ethyl alcohol is useful in the
treatment of methyl alcohol poisoning?
(A. 395, B. 93)
are used in the petit mal epilepsy. (A.
421, B. 139)
0113 E007
Second Year MBBS Examination
II MBBS Pharmacology Paper 1
Time: 2 hours
--- Content provided by FirstRanker.com ---
Max Marks: 401. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
section.
--- Content provided by FirstRanker.com ---
4. Draw diagrams wherever necessary.5. Write legibly.
Section 1
1. Give an account of any TWO of the
following
--- Content provided by FirstRanker.com ---
(10)a) Relevance of pH in drug absorption
(A. 11, B. 13)
b) Pharmacological basis of different
classes of diuretics for various
--- Content provided by FirstRanker.com ---
indications. (A. 579, B. 548)c) Mechanism of action,
pharmacological effects, clinical uses
and adverse reactions of atropine
(A.113, B. 292)
--- Content provided by FirstRanker.com ---
2. Write Short notes of (any three)(12)
a) Mechanism of action and basis
of use of aspirin and clopidogral in
coronary heart disease. (A.629,B. 471)
--- Content provided by FirstRanker.com ---
b) Immunomodulators acting via TNF-alpha in rheumatoid arthritis (A. 212,
B. 1041)
c) Therapeutic uses of cholinesterase
inhibitors (A. 108, B. 283)
--- Content provided by FirstRanker.com ---
d) Pharmacological basis of the use ofinhalational glucocorticoids and
salbutamol in bronchial asthma. (A.
230, B. 361)
3. Discuss Any Three
--- Content provided by FirstRanker.com ---
(12)a) Mechanism of action, therapeutic
uses and adverse effects of
benzodiazepines (A. 402, 405, B. 109)
b) Mechanism of action of synergistic
--- Content provided by FirstRanker.com ---
effect of statins and ezetimibe in thetreatment of dyslipidemia. (A. 636, B.
582)
c) Pharmacological basis of uses and
side effects of ACE- Inhibitors and
--- Content provided by FirstRanker.com ---
AT1-receptor antagonists. (A.562, B.421)
d) Pharmacological basis of use and
dose and duration dependent adverse
effects of phenytoin(A.413,B. 127)
--- Content provided by FirstRanker.com ---
4. Write Answer to the point in two orthree sentences: (any six)
(6)
a) Why timolol but not propranolol is
used in glaucoma? (A. 153, B. 1030)
--- Content provided by FirstRanker.com ---
b) Why certain drug shows first doseresponse (exaggerated response to
first dose)? (A. 142, B. 417)
c) Explain how clonidine controls
diarrhoea and tinismus of diabetic GIT
--- Content provided by FirstRanker.com ---
antonomic neuropathy. (A.566,8. 412)d) How thiopentone sodium in IV bolus
dose acts as an ultra-short acting
general anesthetic? (A.381,B.102)/
Give reasons: Thiopental is preferred
--- Content provided by FirstRanker.com ---
over phenobarbitone for induction ofG.A.
e) Explain why sodium nitroprusside is
contraindicated in patients with renal
impairment? (A. 567, 419)
--- Content provided by FirstRanker.com ---
f) State the main uses of dicyclomine
and propantheline. (A. 117, B. 297)
g) Why ethyl alcohol is useful in the
treatment of methyl alcohol poisoning?
(A. 395, B. 93)
--- Content provided by FirstRanker.com ---
h) Name two antiepileptic drugs whichare used in the petit mal epilepsy. (A.
421, B. 139)
Document Outline
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