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C 58010 (Pages 2+2+1 = 5) Name:........................
Reg. No:................
SECOND PROFESSIONAL M.B.B.S. DEGREE EXAMINATION, JULY 2009
MICROBIOLOGY-Paper II Maximum: 40 Marks
Time: Two Hours
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Answer all the questions.
Draw diagrams wherever necessary.
Answer Sections A and B in separate answer-books.
MCQs should be answered first in the response sheet provided.
Section A
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I. Multiple Choice Questions. Single response type 8 (separate sheet attached). (8 x ¼ = 4 marks)
II. Match the following. Single response type 8 (separate sheet attached). (8 x ¼ = 4 marks)
III. Draw and label:
(a) Rabies virus.
(b) Aspergillus fumigatus. (2 x 1 = 2 marks)
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IV. Short answer questions:
1 What are Mycotoxins ?
2 What is antigenic shift?
3 Differentiate eumycotic mycetoma from actinomycotic mycetoma.
4 Enumerate four parasitic infections in which liver is affected as the target organ. (4 x 1 = 4 marks)
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V. Write short notes on:
1 Histoplasmosis
2 Prophylaxis of poliomyelitis.
3 Free living amoeba. (3 x 2 = 6 marks)
Section B
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VI. Read the following paragraph and answer the following questions :-
A 40 year old man presented with fever, diarrhoea and loss of weight of three months duration. He
gives a history of sexual contact with a commercial sex worker 10 years back. Stool examination by
modified acid fast staining revealed pink coloured cysts. Blood test confirmed the diagnosis.
Turn over
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C 58010
1 What is the likely diagnosis?
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2 What are the aetiological agents that produce intractable diarrhoea in such patients?
3 What are the blood tests to be done to confirm the diagnosis?
4 Classify the antiviral drugs used for treatment. (1+3+3+3 = 10 marks)
VII. Short answer questions:
1 What are prions?
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2 What are dimorphic fungi? Give two examples.
3 What is a continuous cell line? Give two examples.
4 What are dermatophytids? (4x1= 4 marks)
VIII. Write short notes on:
1 Pneumocystis jiroveci.
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2 KFD.
3 M.M.R. vaccine. (3x2=6 marks)
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C 58010
MICROBIOLOGY-Paper II
I. MULTIPLE CHOICE QUESTIONS
Note.-(1) Do not write anything on the question paper.
(2) Write your register number on the answer-sheet provided.
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(3) Select one most appropriate response and encircle the corresponding alphabet against
each question number in the answer-sheet provided
1. Virus commonly causing aseptic meningitis is:
(A) Parvovirus. (B) ECHO virus.
(C) Norwalk virus, (D) Adeno virus.
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2. Presumptive coliform count is usually done to analyse the quality of:
(A) Milk. (B) Water.
(C) Blood. (D) Food.
3. The morphological form of Leishmania donovani seen in peripheral blood of man is:
(A) Amastigotes. (B) Epimastigotes.
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(C) Promastigotes. (D) Trypomastigotes.
4. All of the following viruses are sexually transmitted except:
(A) HIV. (B) HBV.
(C) HPV. (D) Poliovirus.
5. Negri bodies are abundant in:
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(A) Hippocampus. (B) Hypothalamus.
(C) Cerebrum. (D) Pons.
6. Leishmania can be grown in:
(A) Chocolate agar. (B) NNN medium.
(C) Bile salt agar. (D) Loefflers serum slope.
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7. Spores with tubercles or finger like projections are diagnostic of:
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(A) Coccidioidomycosis. (B) Candidiasis.
(C) Histoplasmosis. (D) Crytococcosis.
8. The following are viral haemorrhagic fevers except:
(A) Marburg. (B) Ebola.
(C) Hantaan. (D) EBV. (8 x ¼ = 4 marks).
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C 58010
II. Match the following:-
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MICROBIOLOGY-Paper II
A 1 Schistosoma haematobium (a) Anaemia.
2 Strongyloides stercoralis (b) Keratitis.
3 Ankylostoma duodenale (c) Endemic haematuria.
4 Acanthamoeba (d) Larva currens.
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(e) Otitis media.
B 1 Negri bodies (a) Measles virus.
2 Henderson-Patterson bodies (b) HSV.
3 Warthin-Finkeldy bodies (c) Molluscum contagiosum.
4 Lipshutz bodies (d) Rabies virus.
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(e) Adenovirus.
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