Rajiv Gandhi University of Health Sciences, Karnataka
M.Ch. Degree Examination – 11-Dec-2019
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Time: Three Hours Max. Marks: 100 Marks
GYNECOLOGICAL ONCOLOGY - PAPER – I
Screening and Basic Sciences Pertaining to Gynecologic Oncology
QP Code: 9376
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary. Answer all questions.
LONG ESSAY (These questions carry 10 marks each) 10 x 10 = 100 Marks
- Discuss the role of molecular markers in cervical cancer screening.
- Explain in brief the molecular alterations involved in cancer pathogenesis.
- Discuss hereditary Breast ovarian cancer syndrome.
- What are the types of epithelial ovarian cancer and there molecular basis? What are the germ line mutations which have been implicated?
- Describe the various phases of clinical trials.
- Factors influencing the risk of persistence of HPV infection and progression of CIN.
- How will you follow up a case of vesicular mole? Discuss the role of chemotherapy and surgery in these cases.
- Describe mechanism of DNA repair. Role of PARP inhibitors.
- What are the risk factors for uterine corpus cancer? What are the preventive measures?
- Role of colony stimulating factors in prevention of bone marrow suppression.
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