Rajiv Gandhi University of Health Sciences, Karnataka
D.M. Degree Examination ? 11-Dec-2019
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Time: Three HoursMax. Marks: 100 Marks
PAEDIATRIC NEPHROLOGY - PAPER ? I
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QP Code: 9166
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary. Answer all questions.LONG ESSAY (These questions carry 10 marks each)
10 x 10 = 100 Marks
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1.
Discuss the molecular events in ureteric bud induction and outgrowth and renal branching
morphogenesis.
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2.
Discuss the role of kidney in maintain potassium homeostasis.
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3.Discuss the various methods for genetic testing and indications for genetic testing in children with
renal disease with examples.
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4.How do animal models help in understanding pathobiology of nephrotic syndrome?
5.
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Discuss the indications, procedure and interpretation of water deprivation test.
6.
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Discuss the physiology and development of normal micturition.7.
Discuss the mechanisms of renal drug excretion and clearance.
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8.
List out the entities under collagen type 4 and 3 glomerulopathy and discuss genetics of Alport's
syndrome.
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9.
Discuss various methods of randomization of clinical trials with examples of its use.
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10.Discuss the nomenclature and methods of HLA typing in renal transplantation.
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