Download MBBS TMU 1st Year 2017 MBS103A Biochemistry I Question Paper

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) TMU (Teerthanker Mahaveer University) First Year (1st Year) 2017 MBS103A Biochemistry I Previous Question Paper

MBBS I (First) Professional Examination 2016-17

Course Code: MBS103 Paper ID: 0322208

Biochemistry -I

Time: 2 Hours 40 Minutes

Max Marks: 40

Note: Attempt all questions. Draw proper diagrams to support

your answer.

Part `B'

1.

Discuss various biochemical changes in blood and urine in
a patient, suffering from haemolytic jaundice. (10)

2.

Describe in detail, the synthesis of urea. (10)

3.

Write in detail: (5+5)

a)

Gluconeogenesis

b)

Phenylketonuria

4. a)

Inhibitors of ETC and uncouplers of oxidative
phosphorylation (5)

b)

Homocysteine and it's role in health and disease (5)



MBBS I (First) Professional Examination 2016-17

Roll No.

Student's Name



Student's Signature

Invigilator's Signature



Course Code:MBS103



Paper ID: 0322208

Biochemistry - I

Part `A'



Time: 20 Minutes

Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick () correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.


a)

Alanine transaminase

Q.1

Lipid bilayer is most permeable to:

b)

Aspartate transaminase

a)

Potassium

c)

Lactate dehydrogenase

b)

Sodium

d)

Creatinine phosphokinase

c)

Glucose

d)

Urea

Q.10 Hyperammonemia inhibit TCA cycle by

depleting:

Q.2

All these reactions take place inside the

a)

Oxaloacetate

mitochondria except:

b)

Alpha ketoglutarate



a. Glycolysis

c)

Aspartate

b. Urea cycle

d)

Fumarate

c. Electron transfer chain



d. oxidation of fatty acids

Q.11 End product of action of salivary amylase

is:

Q.3

Starch and Glycogen, both are polymers of:
a)

Mannose

P.T.O.

b)

Alpha Glucose

a)

Mannose

c)

Beta Glucose

b)

Maltose

d)

Fructose

c)

Sucrose

d)

Fructose

Q.4

Which is a fructosan:
a)

Pectin

b)

Chitin

Q.12 Inhibitor of complex IV cytochrome

c)

Inulin

d)

Glycogen

oxidase of E.T.C is :
a)

Cyanide

Q.5

Amino acid, which does not allow the

b)

Antimycin A

formation of -helix:

c)

Dinitrophenol

a)

Glutamate

d)

Malonate

b)

Proline

c)

Lysine

Q.13 Insulin acts on which enzyme is glycolysis:

d)

Histidine

a)

Glucokinase

b)

Hexokinase

Q.6

Following fatty acid does not belong to

c)

Glucose-6 phosphatase

omega-6 series:

d)

Adenylate kinase

a)

Linoleic acid

b)

Arachidonic acid

Q.14 Following are ketogenic except:

a)

Leucine

c)

Gamma linolenic acid

b)

Tyrosine

d) Alpha linolenic acid

c)

Glycerol

d)

Fatty acid

Q.7

Rancidity of fats is due to :
a)

Cyclic hydro carbon

Q.15 Prostaglandins are synthesized in the body

b)

Lysolecithin

from :

c)

Glycosphingolipids

a)

Oleic acid

d)

Cholesterol

b)

Stearic acid

c)

Arachidonic acid

Q.8

Which of the following enzyme is stable at

d)

Palmitic acid

acidic pH:
a)

Pepsin

Q.16 Ammonia is detoxified in brain by the

b)

Trypsin

formation of :

c)

Chymotrypsin

a)

Creatine

d)

Carboxypeptidase

b)

Urea

c)

Glutamine

Q.9

First enzyme to be released in to circulation

d)

None of these

after myocardial infarction:

Q.17 Xanthurenic acid is a product of

metabolism of:
a)

Tryptophan

b)

Glucuronic acid

c)

Xanthine

d)

None of above

Q.18 Maple syrup urine disease is due to

deficiency of:
a)

Decarboxylation

b)

Dehydroxylation

c)

Transamination

d)

Deamination

Q.19 Rate limiting enzyme in heme synthesis:

a)

ALA synthase

b)

ALA dehydratase

c)

Heme synthetase

d)

coproporphyrinogen synthase

Q.20 Major site of action of insulin is :

a)

Muscle

b)

Adipose tissue

c)

Liver

d)

Kidney