Download MBBS TMU 1st Year 2018 MBS103 Biochemistry II Question Paper

Max Marks: 40

Note: Attempt all questions. Draw proper diagrams to support your answer.

Part 'B'

1. Describe chemistry, sources, daily requirement, biochemical functions and deficiency manifestations of vitamin-D. (10)

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2. Discuss the following: (5x2=10)

   1. Liver Function Tests
   2. Lac- Operon

3. Write short notes on the following: (2.5x4=10)

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   1. Tumour markers
   2. Cytochrome P450
   3. Absorption of iron
   4. Balanced Diet

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4. Differentiate between: (2x5=10)

   1. Acidosis and Alkalosis
   2. Fat soluble and water soluble vitamins
   3. PCR and Recombinant DNA technology
   4. Active and Passive immunity

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   5. ELISA and RIA

Roll No.

MBBS I (First) Professional Examination 2017-18

Student's Signature

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Course Code: MBS103

Biochemistry - II

Part 'A'

Time: 20 Minutes

Student's Name

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Invigilator's Signature

Paper ID: 0322242

Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

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3. For answering please use Ball- pen only.

1. Q.1 SDA is highest for:

   1. Lipids
   2. Proteins
   3. Carbohydrates

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   4. Glucose

2. Q.2 Oedema occurs in:

   1. Marasmus
   2. Kwashiorkor

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   3. Both
   4. None

3. Q.3 Element present in salivary protein Gusten:

   1. Zinc

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   2. Iodine
   3. Chromium
   4. Selenium

4. Q.4 Dietary fibres helps:

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   1. Motility of GIT
   2. Reduce incidence of colon cancer
   3. Decrease absorption of cholesterol
   4. All of the above

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5. Q.5 Ferroxidase activity is exhibited by:

   1. Ceruloplasmin
   2. Hemosiderin
   3. Ferritin
   4. Siderophilin -C

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6. Q.6 Keshan disease is due to deficiency of:

   1. Selinium
   2. Manganese
   3. Zinc

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   4. Fluorine

7. Q.7 Anion Gap in healthy adults is :

   1. 20-25 mEq/L
   2. 5-10 mEq/L

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   3. 12-18 mEq/L
   4. 2.5-5.0 mEq/L

8. Q.8 In metabolic acidosis:

   1. Decrease in plasma HCO3

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   2. Increase in plasma HCO3
   3. Increased pCO2
   4. Decreased pCO2

9. Q.9 The normal range of creatinine clearance is:

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   1. 120-135 ml/min
   2. 80-90 ml/min
   3. 180 ml/min
   4. 75 ml/min.

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10. Q.10 Proteins are identified by:

    1. Western blotting
    2. Eastern blotting
    3. Southern blotting
    4. Northern blotting

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11. Q.11 Production of monoclonal antibodies in vitro is by:

    1. PCR
    2. Recombinant DNA technology
    3. Hybridoma Technology

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    4. Blotting Technology

12. Q.12 Cancer causing factors includes:

    1. Life Style
    2. Occupation

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    3. Iatrogenic
    4. All of the above

13. Q.13 In duodenal ulcer:

    1. Basal acid output is elevated

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    2. Maximal acid output is elevated
    3. Both are elevated
    4. BAO and MAO are normal

14. Q.14 Tumour marker specific for ovarian cancer is:

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    1. Beta HCG
    2. CEA
    3. CA-125
    4. AFP

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15. Q.15 Phase -II reactions in metabolism of Xenobiotics involves:

    1. Oxidation
    2. Reduction
    3. Hydroxylation
    4. Conjugation

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16. Q.16 Light chains in Immunoglobulins are of types:

    1. kappa and lambda
    2. alpha and beta
    3. gamma and lambda

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    4. alpha and delta

17. Q.17 Methyl donor in detoxification by conjugation is:

    1. S- adenosyl methionine
    2. Glutathione

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    3. Phosphoadenosyl phosphosulfate
    4. Acetyl Co A

18. Q.18 Natural antibodies are:

    1. IgA

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    2. IgM
    3. IgG
    4. IgE

19. Q.19 Carpal tunnel syndrome is seen in deficiency of:

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    1. Pyridoxine
    2. Thiamine
    3. Niacin
    4. Cyanocobalamine

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20. Q.20 Burning feet Syndrome is manifestation of:

    1. Folic acid deficiency
    2. Pantothenic acid deficiency
    3. Biotin Deficiency
    4. Vitamin E deficiency

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