MBBS I (First) Professional Examination 2018-19
Course Code: MBS103
Paper ID: 03219208
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Biochemistry -I
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support your answer.
Part 'B'
- What is the normal blood glucose level? Discuss the factors regulating blood glucose in the fasting and postparandial states. Write the diagnostic criteria for diabetes mellitus. (10)
- Discuss the biochemical alterations seen in blood and urine in different types of Jaundice. (10)
- Describe the importance of serum enzyme estimations in clinical diagnosis. (10)
- Write short notes on the following: (2x5=10)
- Transport mechanisms of glucose
- Phenylketonuria
- Inhibitors of ETC
- Second messengers
- Ketogenesis
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Roll No.
MBBS I (First) Professional Examination 2018-19
Student's Signature
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Course Code: MBS103
Time: 20 Minutes
Biochemistry - I
Part 'A'
Student's Name
Invigilator's Signature
Paper ID: 03219208
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Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
- Which of the following is not present in human cell membrane:
- Endotoxin
- Cardiolipin
- Proteoglycan
- Lipopolysaccharide
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- All the following are branched chain amino acids except:
- Isoleucine
- Threonine
- Valine
- Leucine
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- Which of the following contains only alpha glycoside linkages:
- Starch
- Cellulose
- Lactose
- Sucrose
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- Which of the following is not a phospholipid:
- Cerebroside
- Sphingomyelin
- Lecithin
- Cephalin
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- N-3 of purine ring is donated by:
- Aspartate
- Ammonia
- Glycine
- Glutamine
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- In a competitive inhibition:
- Km is decreased Vmax remains same
- Km is increased Vmax remains same
- Km is decreased Vmax is increased
- Km is increased Vmax is increased
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- Gluconeogenesis is inhibited by:
- Insulin
- Glucocorticoids
- Glucagon
- Growth hormone
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- Deficiency of glucose-6-phosphate dehydrogenase causes:
- Dicoumarol
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- Fatty liver may be prevented by the following, except:
- Choline
- Lecithin
- The main apoprotein present in chylomicron:
- B100
- E2
- D
- B48
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- Ammonia is trapped in brain by:
- Glutamate dehydrogenase reaction
- Glutamine reaction
- Glutamine Synthetase reaction
- Urea Synthesis cycle
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- Acute intermittent porphyria (AIP) is:
- Characterized by photodermatitis
- An autosomal dominant trait
- Hemolytic anemia is associated
- More common in men than women
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- Serum acid Phosphatase (ACP) level is increased in:
- Excess phosphate intake
- Rickets
- Hepatoma
- Prostatic carcinoma
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- Which of the following is a simple protein:
- Casein
- Insulin
- Hemoglobin
- Tyrosinase
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- Name the defective enzyme in methyl malonyl aciduria:
- Phenylalanine Hydroxylase
- Methyl malonyl CoA mutase
- Propionyl CoA carboxylase
- Cystathionine synthase
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- Valinomycin inhibit oxidative phosphorylation because:
- It inhibits cytochrome oxidase
- It inhibits ATP synthase
- It forms a complex with NADH
- It makes mitochondria permeable to potassium
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- The most potent thyroid hormone:
- T4
- T3
- T2
- T1
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- Amino acid carrier defect is found in:
- Maple Syrup Urine disease
- Alkaptonuria
- Phenylketonuria
- Cystinuria
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- Triglycerides in serum are transported by:
- HDL
- IDL
- LDL
- Chylomicrons
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