Download MBBS TMU 2nd Year 2015 MBS201A Pathology I Question Paper

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MBBS II (Second) Professional Examination 2014-15

Course Code: MBS201

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Paper ID: 0322401

Pathology-I

Time: 2 Hours 40 Minutes

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support your answer.

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Part 'B'

1. Describe Reversible and Irreversible injury. (7)
2. A 70 years old man with complaint of severe backache was found to have multiple punched out lytic lesion on X-ray in skull and lumbar vertebrae.
   1. What is the diagnosis? (1)
   2. Describe all investigations to confirm diagnosis. (2)
   3. Draw labelled diagram of Bone marrow findings. (2)
   4. Write note on Bence Jones proteins. (2)

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3. Write short notes: (2x4=8)
   1. Pathogenesis of Septic Shock
   2. Tumor Markers
   3. Pathogenesis of AIDS
   4. Hypertrophy

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4. Describe briefly: (2x4=8)
   1. Sickle Cell Anemia
   2. CML
   3. Draw well labelled diagram of peripheral smear picture of megaloblastic anemia.
   4. Haemophilia

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Roll No.

MBBS II (Second) Professional Examination 2014-15

Student's Signature

Course Code: MBS201

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Time: 20 Minutes

Pathology-I

Part 'A'

Student's Name

Invigilator's Signature

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Paper ID: 0322403

Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

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2. Transplant rejection is an example of which type of hypersensitivity:
   1. I

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   2. II
   3. III
   4. IV

3. Which of the following is a wear and tear pigment:
   1. Lipofuscin

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   2. Melanin
   3. Hemosiderin
   4. Bilirubin

Ρ.Τ.Ο.

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4. Schilling test is used in the diagnosis of:
   1. Thalassemia
   2. Multiple Myeloma
   3. Hereditary spherocytosis
   4. Megaloblastic Anaemia

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5. Special histo chemical stain for staining amyloid is:
   1. Von Kossa
   2. Masson fontana
   3. Congo red
   4. Veerroeff stain

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6. All of the enzymes are involved in free radical scavenger reactions Except:
   1. Catalase
   2. Superoxide dismutase
   3. Creatine phosphokinase
   4. Glutathione peroxidase

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7. Which of the following vitamins are involved in formation of collagen:
   1. Vitamin A
   2. Vitamin B
   3. Vitamin C
   4. Vitamin D

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8. AML - M3 is characterized by:
   1. Translocation 4,11
   2. Translocation 9, 22
   3. Translocation 9, 11
   4. Translocation 15, 17

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9. Auto Splenectomy is seen in:
   1. Thalassemia
   2. Sickle cell anemia
   3. Carcinoma
   4. Folic acid deficiency

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10. Macrocytic anemia Except
    1. Pernicious anemia
    2. Megaloblastic anemia
    3. Microcytic hypochromic
    4. Normocytic hypochromic

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11. The antigen presenting cells present in skin are called:
    1. Langher cells
    2. Langerhan's cell
    3. Paneth cell
    4. Littoral cell

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12. Syphilis is caused by:
    1. T. palladium
    2. P. Ovale
    3. M. pylori
    4. M. leprae

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13. All are features of ITP Except:
    1. an autoimmune disorder, characterized by formation of anti platelets antibodies
    2. Female preponderance
    3. Spleenomegaly is common in primary ITP
    4. Patients respond to steroid

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14. A 60 yrs old male present with backache Routine hematological investigation revealed Rouleaux formation in smear & raised ESR. X-ray skull revealed lytic lesion in skull. The most likely diagnosis is:
    1. Plasma cell myeloma
    2. B-cell lymphoma
    3. T- cell lymphoma
    4. Metastatic carcinoma

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15. Most common cause of fat embolism is:
    1. Splenic rupture
    2. Fracture neck of femur
    3. Liposarcoma
    4. D. I. C.

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16. An example of Co-dominance is:
    1. Blood group antigen
    2. Spermatic antigen

17. The main bactericidal substance of eosinophils is:
    1. BPI
    2. Major Basic protein

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    3. Lysosome
    4. Lactoferrin

18. The predominant cells within 24 - 48 hours in acute inflammation are:
    1. Neutrophils
    2. Lymphocytes

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    3. Eosinophils
    4. Monocytes

19. Precancerous changes are suggested by:
    1. Aplasia
    2. Hyperplasia

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    3. Dysplasia
    4. Hypertrophy

20. All are example of macrocytic anemia except.
    1. Pernicious anemia
    2. Megaloblastic anemia

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    3. Sickle cell anemia
    4. Folic acid deficiency

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