Download MBBS TMU 2nd Year 2017 MBS203 Pharmacology II Question Paper

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support your answer.

Part 'B'

1. Write short notes on the following: (2x4=8)
   1. Corticosteroids
   2. Oral contraceptives

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   3. DPP-IV inhibitors
   4. Bisphosphonates
2. Explain the pharmacological basis of following: (2x4=8)
   1. 5a-reductase inhibitors in Benign Prostatic Hypertrophy (BPH)
   2. Hormone replacement therapy in Post menopausal women

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   3. Low dose Aspirin as an antiplatelet
   4. Combination of Penicillin & Gentamicin
3. A 60 year old patients presented in emergency with pain in chest associated with sweating and uneasiness. On examination ST elevation was found in ECG. Patient was diagnosed a case of Myocardial Infarction (MI). Answer the following: (7)
   1. Classify Antianginal drugs
   2. Write MOA of Nitrates, uses and ADRS

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   3. Treatment of MI
   4. Post MI treatment and advice
4. Classify antiretroviral drugs. Explain the guidelines for Highly Active Antiretroviral Therapy (HAART). Write a short note on Post exposure prophylaxis in HIV positive patient. (7)

Roll No.

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MBBS II (Second) Professional Examination 2016-17

Student's Signature

Student's Name

Invigilator's Signature

Course Code: MBS203

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Time: 20 Minutes

Pharmacology-II

Part 'A'

Paper ID: 0322412

Max Marks: 10

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Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

1. Thiazides cause all except:
   1. Hyperglycemia
   2. Increased calcium excretion

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   3. Hyperuricemia
   4. Useful in congestive heart failure
2. The primary indication of tamoxiphen citrate is:
   1. Female infertility
   2. Endometrial carcinoma

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   3. Carcinoma breast
   4. Endometriosis
3. Mifepristone (RU- FirstRanker.com)
   1. Antiprogestin
   2. Antiestrogen

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   3. Antiandrogen
4. HMG-CoA reductase inhibitor is:
   1. Rosuvastatin
   2. Clofibrate
   3. Gemfibrozil

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   4. Enalapril
5. Antidote for heparin is:
   1. Vit. K
   2. Protamine
   3. EDTA

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   4. Desferioxamine
6. All of the following statements regarding verapamil are true Except:
   1. It blocks L-type calcium channels
   2. It relaxes coronary artery smooth muscle
   3. It increases heart rate

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   4. It depresses cardiac contractility
7. Select the drug which is an 'inodilator' beneficial in refractory congestive heart failure:
   1. Nicorandil
   2. Amiodarone
   3. Amrinone

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   4. Enalapril
8. Which of the following antiplatelate drugs is not given by oral route:
   1. Aspirin
   2. Clopidogrel
   3. Ticlopidine

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   4. Abciximab
9. Aminoglycosides have the following unwanted effects:
   1. Pancytopenia
   2. Hepatotoxicity
   3. Ototoxicity, nephrotoxicity

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   4. Irritation of gastrointestinal mucosa
10. The primary route of administration of insulin is:
    1. Intradermal
    2. Subcutaneous
    3. Intramuscular

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    4. Intravenous
11. Rifampin has the following unwanted effect:
    1. Dizziness, headache
    2. Loss of hair
    3. Flu-like syndrome

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    4. Hyperuricemia
12. Which of the following antianginal agents is a beta blocker:
    1. Dipyridamole
    2. Verapamil
    3. Atenolol

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    4. Minoxidil
13. The drug which should not be administered to patients taking potassium supplements:
    1. Hydrochlorothiazide
    2. Spironolactone
    3. Furosemide

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    4. Neither of the above
14. The daily dose of estrogen for hormone replacement therapy in postmenopausal women is:
    1. Same as for contraception
    2. Higher than that for contraception
    3. Lower than that for contraception

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    4. Variable depending on the age of the women
15. Tick the drug, inhibiting viral reverse transcriptase:
    1. Zidovudine
    2. Vidarabine
    3. Rimantadine

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    4. Gancyclovir
16. Which of the following vitamins is given with Isoniazid in the treatment of tuberculosis:
    1. Nicotinic acid
    2. Riboflavin
    3. Pyridoxine

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    4. Ascorbic acid
17. Which is not an oral anti-coagulant:
    1. Dicumarol
    2. Warfarin
    3. Heparin

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    4. Phenindione
18. MOA of penicillin is:
    1. Inhibits cell membrane synthesis
    2. Inhibits cell wall synthesis
    3. Inhibits mitochondrial function

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    4. Inhibits protein synthesis
19. Which is not a 3rd generation cephalosporin:
    1. Ceftriaxone
    2. Cephalexin
    3. Cefotaxime

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    4. Cefoperzone
20. Chloroquine in malaria acts on:
    1. Erythrocytic cycle
    2. Exo-erythrocytic cycle
    3. Liver

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    4. Tissue schizonts