Download MBBS TMU 2nd Year 2015 MBS202A Microbiology I Question Paper

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MBBS II (Second) Professional Examination 2014-15

Course Code: MBS202

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Paper ID: 0322405

Microbiology-I

Note: Attempt all questions. Draw proper diagrams to support your answer.

1. Part 'B'

   A 20 years old male has come with fever of 10 days duration along with mild coated tongue and splenomegaly. (1+1+4+1=7)

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   1. What is the most probable diagnosis?
   2. Name the bacteria causing this condition.
   3. Discuss the tests you would like to carry out.
   4. Name different antibiotic choices available to treat the condition.

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2. Define hypersensitivity reaction. What are different hypersensitivity reactions? Discuss type-I hypersensitivity reaction with reference to mechanism and manifestations. (1+1+5=7)

3. Describe briefly: (8+8=16)

   1. Mechanisms of genetic transfer in bacteria
   2. Etiology & pathogenesis of cholera

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MBBS II (Second) Professional Examination 2014-15

Microbiology-I

Part 'A'

Max Marks: 10

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Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

1. Which one of the following specimen is best for diagnosis of Mycoplasma pneumonia:
   1. Sputum
   2. Throat swab

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   3. Bough plate
   4. Lung aspirate
2. Which of the following spirochaetes can be seen by compound microscope:
   1. Treponema
   2. Leptospira

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   3. Borrelia
   4. None of the above
3. The concentration of H₂SO₄ used for decolorization of Mycobacterium leprae is:
   1. 20%
   2. 1%

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   3. 5%
   4. 0.5%
4. Which one of the following is not strictly microaerophilic:
   1. Nocardia
   2. Actinomyces

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   3. Helicobacter pylori
   4. Neisseria gonorrheae
5. The usual cut off titre of Widal test for diagnosis typhoid fever is:
   1. 1:20
   2. 1:40

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   3. 1:80
   4. 1:160
6. Which of the following immunoglobulin is better marker for diagnosing acute infections:
   1. IgG
   2. IgM

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   3. IgD
   4. IgE
7. Which of the following bacteria is the commonest cause of neonatal meningitis:
   1. Escherichia coli
   2. Haemophilus influenzae

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   3. Streptococcus pyogenes
   4. Staphylococcus aureus
8. An infection contracted due to procedures in the hospital is called as:
   1. Nosocomial
   2. Iatrogenic

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   3. Mycoplasma pneumoniae
   4. Rickettsiae prowazekii
9. Which of the following medium is a selective medium for Salmonella Typhi:
   1. Tellurite blood agar
   2. TCBS

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   3. Wilson Blair medium
   4. Selenite F broth
10. The substance which induces proliferation of lymphocytes is called as:
    1. Antigen
    2. Mitogen

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    3. Hapten
    4. Adjuvant
11. Montoux test is an example of:
    1. Type I hypersensitivity reaction
    2. Type IV hypersensitivity reaction

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    3. Type II hypersensitivity reaction
    4. Type III hypersensitivity reaction
12. In Mycobacterium tuberculosis multidrug therapy is administered to avoid development of drug resistance through:
    1. Plasmids
    2. Transformation

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    3. Mutation
    4. Bacteriophages
13. Which of the following is the most common cause of urinary tract infection:
    1. Coagulase negative Staphylococci
    2. Neisseria gonorrhoeae

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    3. Escherichia coli
    4. Citrobacter freundii
14. Which of the following vaccine must be taken before joining a diagnostic laboratory:
    1. Small pox
    2. Polio

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    3. Hepatitis B
    4. Dengue
15. Which of the following bacteria does not cause dysentery:
    1. Vibrio parahaemolyticus
    2. Vibrio cholerae

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    3. Yersinia enterocolitica
    4. Shigella dysenteriae
16. Which of the following is not an enriched medium:
    1. Loeffler's serum slope
    2. Sabouraud's dextrose agar

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    3. Chocolate agar
    4. Blood agar
17. Usual incubation period for the growth Mycobacterium tuberculosis is:
    1. 3-8 weeks
    2. 3-8 days

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    3. 3-8 hours
    4. 3-8 months
18. Which of the following medium is poured after melting without autoclaving:
    1. Blood agar
    2. TCBS

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    3. Nutrient agar
    4. McConkey agar
19. Which one of the following media is used for rapid growth of Corynebacterium diphtheriae:
    1. Mueller Hinton agar
    2. Blood agar

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    3. Loeffler's serum slope
    4. Tellurite blood agar