Download MBBS TMU 2nd Year 2019 MBS201 Pathology I Question Paper

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support your answer.

Part 'B'

1. Write about pathophysiology, peripheral smear findings and lab investigation of sickle cell anemia. (7)

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2. Describe healing of wound by primary intention and secondary intention. (7)

3. Write short notes on: (4+4)

   1. DIC
   2. FAB Classification of acute leukemia

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4. Write short notes on: (4+4)

   1. Chemotaxis
   2. Metaplasia

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Roll No.

MBBS II (Second) Professional Examination 2018-19

Student's Signature

Course Code: MBS201

Time: 20 Minutes

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Pathology-I

Part 'A'

Student's Name

Invigilator's Signature

Paper ID: 03218201

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Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

1. Q.1 ______ is associated with angiogenesis

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   1. Firsdankekingiogenesis
   2. Collagen deposition

2. Q.2 Paraneoplastic manifestation of gastric carcinoma is:

   1. AcanthosisNigricans

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   2. Dermatomyositis
   3. Hypoglycemia
   4. Hypercalcemia

3. Q.3 Appearance of Zebra bodies on electron microscopy is diagnosis of:

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   1. Niemann Pick disease
   2. Gaucher disease
   3. TaySach disease
   4. Glycogen storage disease

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4. Q.4. Which of the following is a stable cell;

   1. Cardiac myocyte
   2. Neurons.
   3. Hepatocyte
   4. Gastro intestinal epithelium

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5. Q.5 Type of amyloid protein seen in patients with long term hemodialysis is:

   1. TTR
   2. β2 amyloid
   3. β amyloid

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   4. AL Protein

6. Q.6 Gumma is a feature of which type of syphilis:

   1. Primary
   2. Secondary

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   3. Tertiary
   4. Congenital

7. Q.7 Presence of lanugo hair and fat in the pulmonary microcirculation is a feature of:

   1. Fat embolism

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   2. Amniotic fluid embolism
   3. DIC
   4. Caisson's disease

8. Q.8 The distinctive nuclear and cytoplasmic structural alterations in apoptosis are due to:

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   1. Caspase
   2. Lipase
   3. Amylase
   4. Hydrolase

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9. Q.9 Downey cells are seen in the peripheral blood in which condition:

   1. Malaria
   2. Kalaazar
   3. Dengue
   4. Common

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10. Q.11 Presence of Birbeck granules in cytoplasm is characteristic of:

    1. Primary myelofibrosis
    2. Myelodysplastic syndrome
    3. Langerhan cell histiocytosis

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    4. Polycythemia vera

11. Q.12 What is the ideal temperature for storing Platelet concentrates:

    1. 2-8 °C
    2. 20-24°C

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    3. 37°C
    4. -50°C

12. Q.13 Reduced serum haptoglobin is a feature of:

    1. Iron deficiency anemia

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    2. Hemolytic anemia
    3. Megaloblastic anemia
    4. Anemia of chronic disease

13. Q.14 Cryoprecipitate is used for the treatment of:

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    1. Hemophilia
    2. Iron deficiency anemia
    3. Aplastic anemia
    4. Multiple myeloma

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14. Q.15 Acid Phosphatase positivity is seen in which acute leukemia:

    1. AML-M5
    2. AML-M6
    3. B-ALL
    4. T-ALL

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15. Q.16 All the following are features of extravascular hemolytic anemia except:

    1. Jaundice
    2. Splenomegaly
    3. Hemoglobinuria

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    4. Anemia

16. Q.17 Erythropoietin is secreted by which cells of the kidney:

    1. Mesangial cells
    2. Interstitial cells

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    3. Endothelial cells
    4. Tubular cells

17. Q.18 Which of the following histological subtype of Hodgkin lymphoma is not associated with EBV infection:

    1. Mixed cellularity

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    2. Nodular sclerosis
    3. Lymphocyte rich
    4. Lymphocyte depleted

18. Q.19 Increased susceptibility to pyogenic infections and coarse lysosomal granules in Neutrophils are seen in:

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    1. PelgerHuet anomaly
    2. Chediak Higashi anomaly
    3. Chronic granulomatous disease
    4. Common variable immune-deficiency

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19. Q.20 All the following are B cell lymphomas except:

    1. Burkitt lymphoma
    2. Mycosis Fungoides
    3. Mantle cell lymphoma
    4. Follicular lymphoma

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