Download MBBS TMU 2nd Year 2019 MBS203 Pharmacology I Question Paper

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MBBS II (Second) Professional Examination 2018-19

Course Code: MBS203

Paper ID: 03218205

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Pharmacology-I

Time: 2 Hours 40 Minutes

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support your answer.

Part 'B'

1. Classify adrenergic drugs. Discuss important pharmacological actions, adverse effects & uses of adrenaline. (7)

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2. Enumerate local anesthetics. Discuss mechanism of action, important methods & uses of Lignocaine. (7)
3. Write short notes on: (2x4=8)
   1. Drug tolerance
   2. Therapeutic index
   3. Bio availability
   4. Enterohepatic Circulation

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4. Write pharmacotherapy of the following conditions: (2x4=8)
   1. Acute salicylate poisoning
   2. Organo Phosphorous Poisoning
   3. Acute iron poisoning
   4. Peptic ulcer

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Roll No.

Student's Name

MBBS II (Second) Professional Examination 2018-19

Course Code: MBS203

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Paper ID: 03218205

Time: 20 Minutes

Pharmacology-I

Max Marks: 10

Part 'A'

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Student's Signature

Invigilator's Signature

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

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1. Which of the following is alpha 2 Agonist:
   1. Phentolamine
   2. Terazosin
   3. Clonidine
   4. Pindolol

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2. Which of the following is proton pump inhibitor:
   1. H. Pylori ulcer
   2. GERD
   3. Duodenal ulcer
   4. All of the above

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3. Vasomotor reversal of Dale phenomenon is shown by which drug:
   1. Adrenaline
   2. Isoprenaline
   3. Noradrenaline
   4. All

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4. Which Beta Blocker is having ultra short action:
   1. Atenolol
   2. Nadolol
   3. Bisoprolol
   4. Esmolol

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5. Prior to an operation to remove a pheochromocytoma which of the following should be given to the patient:
   1. Prazosin
   2. Phenoxy benzamine
   3. Atenolol
   4. None of the above

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6. Preferred drug for COPD:
   1. Theophyline
   2. Ipratropium bromide
   3. Salbutamol
   4. Adrenaline

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7. Selective β2 agonists are preferred in bronchial asthma over to Isoprenaline:
   1. Potent bronchodilator
   2. Less palpitation
   3. Longer duration
   4. All of the above

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8. Which one is mucolytics:
   1. Bromhexine
   2. Ambroxal
   3. Acetylcystine.
   4. All of the above

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9. Which of the following drug used in the treatment of gout acts by preventing the migration of granulocytes:
   1. Allopurinol
   2. Sulfinpyrazone
   3. Colchicine
   4. Indomethacin

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10. Following action of aspirin manifested only at Higher dose except:
    1. Analgesic
    2. Antipyretic
    3. Anti-inflammatory
    4. Anti-platelet

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11. Side effects of aspirin include All EXCEPT:
    1. Salicylism (vomiting, tinnitus, decreased hearing, and vertigo)
    2. Gastric ulcers and upper gastrointestinal bleeding
    3. Gastric upset (intolerance)
    4. Myocardial infarction

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12. Which of the following opioid analgesics is a Synthetic drug:
    1. Codeine
    2. Morphine
    3. Pethidine
    4. All of the above

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13. Following one has high first pass metabolism:
    1. Isoprenaline
    2. Lignocaine
    3. All of the above
    4. None of the above

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14. Naloxone is antagonists of:
    1. Morphine
    2. Benzodiazepine
    3. Barbiturate
    4. None of the above

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15. Over to dopamine, levodopa and carbidopa in combination is given because of:
    1. Plasma t½ of levodopa is prolonged
    2. Cardiac complication are minimum
    3. On-off effect is minimum
    4. All of the above

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16. Following anti cholinergic drug is preferred as anti parkinsonian drug:
    1. Trihexyphenidyl
    2. Atropine
    3. Scopolamine
    4. All of the above

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17. Following anti psychotics drug is preferred for schizophrenia:
    1. Risperidone
    2. Chlorpromazine
    3. Haloperidol
    4. All of the above

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18. Following one is selective serotonin reuptake inhibitors:
    1. Citalopram
    2. Escitalopram
    3. Fluoxetine
    4. All of the above

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