Download MBBS TMU 2nd Year 2016 MBS202A Microbiology I Question Paper

MBBS II (Second) Professional Examination 2015-16

Course Code: MBS202

Paper ID: 0322405

Microbiology-I

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Time: 2 Hours 40 Minutes

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support your answer.

Roll No.

Part 'B'

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1. Define Urinary Tract Infection, Enumerate bacteria causing UTI. Describe the laboratory diagnosis of UTI under the following headings: specimen collection and transport, screening tests, processing for culture and interpretation of culture report. (7)

2. Define sterilization. Enumerate methods of sterilization. Discuss the principle, functioning and control of an autoclave. (7)

3. Write short notes on: (4x2=8)

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   1. Laboratory diagnosis of pulmonary tuberculosis
   2. Structure and function of IgM

4. Write short notes on: (4x2=8)

   1. Virulence factors and diseases caused by Staphylococcus aureus

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   2. Structure, function and demonstration of bacterial capsule

MBBS II (Second) Professional Examination 2015-16

Student's Signature

Course Code: MBS202

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Paper ID: 0322405

Microbiology-I

Part 'A'

Time: 20 Minutes

Student's Name

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Invigilator's Signature

Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.

2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.

3. For answering please use Ball- pen only.

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9. Bacterial count between 10³ and 10⁵ CFU per mL

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Bacterial count<10² CFU per mL

2. Most common bacterial cause of sore throat is:

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   1. Group D streptococci
   2. Group C streptococcus
   3. Group A streptococcus
   4. Group B streptococcus

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P.T.O.

10. One of the anaerobic spore bearing bacilli gives a positive Nagler reaction:

    1. Clostridium tetani
    2. Clostridium difficile
    3. Clostridium botulinum

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    4. Clostridium perfringens

3. The causative agent of Donovanosis is:

   1. Haemophilus ducreyi
   2. Klebsiella granulomatis

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   3. Candida albicans
   4. Mycoplasma hominis

11. Chinese letter arrangement of bacilli is a characteristic feature of:

    1. Corynebacterium diphtheriae

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    2. Mycobacterium tuberculosis
    3. Mycobacterium gordoniae
    4. Corynebacterium ulcerans

4. Type 1 Hypersensitivity reaction is mediated by:

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   1. IgG
   2. IgM
   3. IgA
   4. IgE

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12. One of the following bacteria is capsulated:

    1. Corynebacterium diphtheriae
    2. Enterococcus faecalis
    3. Shigella dysenteriae
    4. Streptococcus pneumoniae

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5. Which cell wall component of Staphylococcus aureus takes part in Coagglutination:

   1. Protein A
   2. Beta Lysin
   3. Clumping factor

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   4. Peptidoglycan

13. Antistreptolysin O test (ASO) is used in the diagnosis of:

    1. Acute rheumatic fever
    2. Typhoid fever

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    3. Q fever
    4. Relapsing fever

6. Multidrug resistance tuberculosis (MDR-TB) is due to M.tuberculosis strain:

   1. Resistance to Niacin only

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   2. Resistance to Rifampicin and Ethambutol
   3. Resistance to Niacin and Streptomycin
   4. Resistance to both Niacin and Rifampicin

16. One of the following immunoglobulins is the most efficient to produce agglutination reaction:

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    1. IgG
    2. IgM
    3. IgA
    4. IgE

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7. One of the stage of whooping cough is most infective:

   1. Paroxysmal stage
   2. Catarrhal stage
   3. Convalescent stage
   4. None of the above

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17. Chemical nature of Endotoxin is:

    1. Lipopolysaccharide
    2. Protein
    3. Carbohydrate

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    4. Dextran

8. Widal test is used in the diagnosis of:

   1. S. typhi
   2. Escherichia coli

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   3. Proteus vulgaris
   4. Vibrio cholera

18. Drug resistance in Mycobacterium tuberculosis is due to:

    1. Transformation

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    2. Conjugation
    3. Transduction
    4. Mutation

14. Toxic shock syndrome is caused by:

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    1. Staphylococcus epidermidis
    2. Staphylococcus saprophyticus
    3. Staphylococcus aureus
    4. Staphylococcus intermedius

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19. Catalase test is negative in:

    1. Streptococcus pyogenes
    2. Staphylococcus aureus
    3. Escherichia coli
    4. Klebsiella pneumoniae

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15. Classical pathway of the complement is activated by:

    1. Antigen
    2. Antibody
    3. Endotoxin

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    4. Antigen-antibody complex

20. One of the followings is used commercially for sterilisation of disposable plastic items:

    1. Autoclave
    2. Ethyl alcohol

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    3. Ethylene oxide
    4. Gluteraldehyde