Download DNB 2019 June PHARMACOLOGY PHARMACOLOGY PAPER 1 Question Paper

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FINAL EXAM

JUNE 2019

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PHARMACOLOGY

PAPER-I

Time: 3 hours PHARM/J/19/34/1 Max. Marks:100

Important Instructions:

• Attempt all questions in order.

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• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.

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• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. a) Nonlinear pharmacokinetics. 5+5
   b) Volume of distribution.

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2. Define essential medicines. Discuss the criteria for 3+(4+3)
   selection of essential medicines with special emphasis on
   challenges faced in India.
3. Define plasma half-life of a drug. Discuss factors which 2+4+4
   modify half-life of a drug. Discuss clinical implications of
   

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   half-life.
4. Determination of drug levels in body fluids. 10
5. What is pharmacogenomics? Discuss its impact on 4+6
   pharmacotherapeutics.
6. a) Voltage gated ion channels. 5+5
   

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   b) Autoreceptors.
7. Discuss briefly prescribing consideration in physiological 10
   and pathological conditions with suitable examples.
8. a) Pharmacoeconomics and its role in Indian health care 5+5
   system.
   

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   b) Counterfeit medication and their health risks.
9. Functions and clinical significance of P-glycoproteins. 5+5
10. a) Herb-drug interactions. 5+5
    b) Biased agonism with examples.

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.

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