Download Diplomate in National Board (DNB) 2019 Dec 2019 Dec PHARMACOLOGY PAPER III Previous Question Papers
DECEMBER 2019
PHARMACOLOGY
PAPER-III
Time: 3 hours PHARMlD/19/34/lll
Max. Marksz100
Important instructions:
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space
Answer all the parts of a single question together
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw tabIe/diagrams/flowcharts wherever appropriate.
0 O O O O O O 0
Write short notes on:
1. Give an outline of experimental methods for evaluating antiepileptic drugs. 10
2. Discuss in details the pharmacological screening of a natural product with 8+2
potential antihypertensive activity. How would you locate the site of
antihypertensive action?
3. How would you design the toxicity studies for new synthetic compounds with 10
anti?inflammatory activity?
4. Importance of biostatistics in medical experimentations. 10
5. Discuss the considerations and approach to calculate minimum sample size 10
for clinical trial of a new drug in comparison with standard therapy.
6. Why the measures of Confidence Interval (Cl) should be added with p-value 10
during writing result of a clinical research?
7. a) Attributableriskreduction. 5+5
b) Multivariate regression analysis.
8. Explain with examples ?Safety Pharmacology? studies in new drug 10
development.
9. Briefly outline the laboratory animal facility as per CPCSEA. 10
10. Write a commentary on per?protocol vis-??vis intention to treat analysis. 10
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POSSESSION/USE OF CELL PHONES OR ANY SUCI I ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXA MINA TION HA L1,.
This post was last modified on 17 April 2020