Download DNB 2019 Dec 2019 Dec MEDICAL ONCOLOGY PAPER III Question Paper

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FINAL EXAM DECEMBER 2019

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Time: 3 hours

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NATIONAL BOARD OF EXAMINATIONS

MEDICAL ONCOLOGY

PAPER-III

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Max. Marks:100

Important Instructions:

• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.

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• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

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Write short notes on:

1. A 25-year-old male presents with left supraclavicular lymphadenopathy in the outpatient department.
   1. Write the differential diagnosis. (2+4+4)
   2. Risk stratification and staging of testicular germ cell tumours.
   3. Management of high risk germ cell tumour of testis.

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2. 1. Write an algorithm for the treatment of metastatic breast cancer (MBC). (3+4+3)
   2. Describe management of hormone receptor positive HER2 negative MBC.
   3. Cyclin dependent kinase inhibitors.
3. 1. List the oncological emergencies that may be associated in a patient with acute promyelocytic leukemia(APML). (3+4+3)

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   2. Enumerate the various supportive treatments that need to be provided to a patient with APML
   3. Management of low risk APML.
4. 1. Differential diagnosis and evaluation of small round cell tumour in a child. (3+4+3)
   2. Diagnosis and staging of neuroblastoma.

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   3. Management of stage 4S neuroblastoma.
5. 1. Histology specific differential response to chemotherapy/targeted therapy in advanced soft tissue sarcoma. (5+3+2)
   2. Systemic therapy of metastatic uterine leiomyosarcoma.
   3. Desmoids tumour.

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6. 1. Evaluation of a patient presenting with metastatic liver disease. (3+5+2)
   2. Describe various liver directed therapies in liver metastasis.
   3. Complications of radiofrequency ablation.

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7. 1. Waldenstrom’s macroglobulinemia. (3+4+3)
   2. POEMS syndrome.
   3. Systemic AL (immunoglobulin light chain) amyloidosis.
8. 1. Etiological factors in cancer of urinary bladder. (3+3+4)

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   2. Diagnosis and staging of cancer of urinary bladder.
   3. Management of stage | urinary bladder cancer.
9. 1. Grading and staging of follicular lymphoma. (3+3+4)
   2. Indication of treatment in follicular lymphoma.

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   3. Management of newly diagnosed stage [V grade 2 follicular lymphoma.
10. 1. Stem cell harvesting. (3+2+3+2)
    2. Cryopreservation of stem cells.
    3. Conditioning regimens.

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    4. Graft versus host disease.

POSSESSION/USE OF CELL PHONES OR ANY ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.