Download DNB 2017 Dec PHYSIOLOGY PHY Paper I Question Paper

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PHYSIOLOGY

PAPER - I

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Time : 3 hours

Max. Marks : 100

Important instructions:

• Attempt all questions in order.
• Each question carries 10 marks.

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• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.

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• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. a) Define homeostasis. 1
   b) Explain in brief characteristic features of negative and feedback mechanisms. Give appropriate examples. 6
   c) Add a note on Feed Forward Control system. 3

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2. a) Illustrate with the help of diagram /flow chart the formation of temporary and permanent haemostatic plugs. 5
   b) Components and physiological importance of Fibrinolytic system. 3
   c) Pathophysiology of disseminated intravascular coagulation. 2
3. a) Enumerate various components of Cytoskeleton. Explain in brief the structure and function of each. 6
   b) List the major molecular motors and their functions. 4

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4. a) Role of folic acid in erythropoiesis 4
   b) Features and laboratory investigations of folic acid deficiency anemia (3+3)
5. a) Steps involved in production of hyperosmotic renal medullary interstitium. 5
   b) Role of vasa-recta in excreting concentrated urine 3
   c) Free-water clearance 2

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6. a) Define Glomerular Filtration Rate (GFR) 1
   b) Determinants of GFR 3
   c) Autoregulation of GFR and renal blood flow 3
   d) Measurement of GFR 3
7. a) What is Mononuclear Phagocytic System? 2
   

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   b) What are its components, their location and functions in human body? 8
8. a) Define ageing 1
   b) Theories of ageing 5
   c) Anti-ageing therapies 4
9. a) Sampling techniques in medical research 6
   

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   b) ANOVA 4
10. a) What are the factors affecting metabolic rate? 6
    b) Obesity 4

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