Download DNB 2017 Dec ENDO ENDO PAPER I Question Paper

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NATIONAL BOARD OF EXAMINATIONS

DECEMBER 2017

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ENDOCRINOLOGY

PAPER — I

ENDQO/D/17/07/1

Time : 3 hours Max. Marks :100

Important instructions:

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• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.

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• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Describe the steps in expression of a protein encoding gene and subcellular structure of cells that secrete protein hormones. (5+5)

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2. Various assays for hormone assessment. (10)
3. What are confidence intervals, power and type I & II error probability? (3+3+4)
4. Adipose tissue as an endocrine organ. (10)
5. Disposition index and its relation to insulin resistance. (5+5)
6. Endocrine maternal adaptation to pregnancy. (10)

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7. 46, XY disorders of sex development. (10)
8. Monogenic causes of obesity and obesity syndromes due to chromosomal re-arrangements. (5+5)
9. Quality control systems and investigation of discordant test values. (5+5)
10. Assessment of B cell reserve. (10)

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POSSESSION / USE OF CELL PHONE IS NOT PERMITTED INSIDE THE EXAMINATION HALL.