Download DNB 2017 Dec MED ONCO MED ONCO PAPER II Question Paper

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DECEMBER 2017

MEDICAL ONCOLOGY

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PAPER - II

Time : 3 hours MED.ONCO./D/17/17/1l Max. Marks :100

Important instructions:

1. Attempt all questions in order.
2. Each question carries 10 marks.

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3. Read the question carefully and answer to the point neatly and legibly.
4. Do not leave any blank pages between two answers.
5. Indicate the question number correctly for the answer in the margin space.
6. Answer all the parts of a single question together.
7. Start the answer to a question on a fresh page or leave adequate space between two answers.

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8. Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Describe about breast cancer under following headings. 3+7
   1. Her 2 neu gene testing: Immunohistochemistry versus FISH.
   2. Use of Her-2 neu targeted therapy in neo-adjuvant, adjuvant and metastatic setting.

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2. 1. List the investigation in a suspected case of chronic myeloproliforative disease (CMPD) 3+3+4
   2. Molecular biology of Ph negative CMPD
   3. Ruxolitinib: Indications and side‘effects
3. 1. Lugano staging of non Hodgkin’s lymphoma 4+6

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   2. Describe criteria for response assessment in lymphoma
4. 1. Pathology of gastric carcinoma 4+6
   2. Treatment both chemotherapy and targeted for unresectable gastric carcinoma

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5. 1. List various cytotoxic agents associated with severe emesis. 3+4+3
   2. Prevention and treatment of chemotherapy induced nausea and vomiting with various agents.
   3. Explain their mechanism of action and side effects.
6. 1. Pathology of medulloblastoma. 3+3+4

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   2. Molecular classification of medulloblastoma
   3. Staging of medulloblastoma and salient investigations for its staging.
7. Role of check point inhibitors in non small cell lung cancer (NSCLS) 3+4+3
8. Algorithm for first time treatment of metastatic NSCLS 5+2+3

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9. Role of ceritinib and alectinib in NSCLC with brain metastasis 4+3+3
10. 1. Pathology and staging of prostate cancer. 3+4+3
    2. What is androgen resistant prostate cancer?
    3. Chemotherapy indications in prostate cancer with ‘supporting indications’.

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11. Pathology of Rhabdomyosarcoma.
12. Cytogenetic/ Translocation studies in sarcoma: mention tumours where it is useful in diagnosis
13. Huvos grading in osteosarcoma
14. Grading of pancreatic neuro-endocrine tumours.
15. Utility of nuclear medicine for diagnosis and treatment of neuroendocrine tumour.

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16. Chemotherapy of neuroendocrine tumor.

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.

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