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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
PHARMACOLOGY
PAPER - II
PHARM/D/16/34/1l
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Time : 3 hoursMax. Marks :100
Important instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
- a) Mention the various classes of anti-depressant drugs along with 4+(2+2+2) examples for each class.
b) Enumerate the mechanism(s) of actions, uses and side effects of TCAs. - a) Pharmacotherapy of MDR & XDR tuberculosis. 5+5
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b) Adverse effects, precautions and important drug interactions of rifampicin. - Principle, applications and limitations of: 5+5
a) HPLC
b) ELISA - a) Enumerate dual PPAR agonists. 2+(3+2+3)
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b) Mechanisms of action, advantages and therapeutic potential of dual PPAR agonists. - a) Enumerate the different preparations and advantages of newer 5+5 insulins.
b) Role of incretin based therapy for diabetes mellitus. - a) Uses and side effects of chloroquine. (2+2)+6
b) Pharmacotherapy of chloroquine resistant malaria. - a) Mechanism of action, uses and side effects of NSAIDs. (2+2+2)+4
b) Enumerate DMARDs used in rheumatoid arthritis. - a) Classify drugs used in the treatment of bronchial asthma. 4+(2+2+2)
b) Advantages, precautions and side effects of inhalational therapy in bronchial asthma. - a) Pharmacotherapy of CHF. 5+5
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b) Role of Angiotensin Receptor Neprilysin Inhibitor (ARNI) in CHF. - a) Mechanism of action and uses of corticosteroids. (2+4)+4
b) Side effects of long term corticosteroid therapy.
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POSSESSION / USE OF CELL PHONE IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
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