Download DNB 2016 Dec GASTROENTEROLOGY PAPER 2 Question Paper

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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

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Time : 3 hours
Max. Marks :100

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Important instructions:

• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.

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• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

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1. a) Role of antiviral treatment for hepatocellular carcinoma (HCC) prevention. 3+3+4
   b) Integration of genomic information in the clinical management of HCC.
   c) Prognosis prediction and staging.
2. a) lgG4 related sclerosing cholangitis. 2+2+6
   b) IgG4 related autoimmune hepatitis.
   

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   c) Current concepts and diagnosis of IgG4 related pancreatitis.
3. a) Definition and diagnosis of acute-on-chronic liver failure (ACLF). 2+2+3+3
   b) Inflammatory response and immune function in ACLF.
   c) Prognosis and biomarkers in ACLF.
   d) Management of ACLF.

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4. a) Diagnosis of drug induced-liver injury (DILI). 3+3+4
   b) Drug induced hepatic steatosis.
   c) Anti-tuberculosis therapy induced DILI.
5. Regarding antiviral therapy of Hepatitis C: 4+4+2
   a) Interferon-free strategies with a nucleoside/nucleotide analogue.
   

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   b) Interferon-free strategies without a nucleoside/nucleotide analogue.
   c) Interferon-free regimens in the liver transplant setting.
6. a) Immunopathogenesis of Hepatitis E virus (HEV). 3+4+3
   b) HEV infection in immunosuppressed patients: Natural history and therapy.
   c) Hepatitis E vaccine.

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7. Write the following in relation to pancreatic calculi:
   a) Composition. 2+2+2+2+2
   b) Endoscopic therapy.
   c) Extracorporeal shock wave lithotripsy.
   d) Pancreatoscopy.
   

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   e) Role of Surgery.
8. Write the following clinical perspectives on sphincter of Oddi dysfunction.
   a) Definition and consensus criteria. 3+2+2+3
   b) Pharmacologic therapy.
   c) Endoscopic therapy.
   

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   d) Current state of knowledge.
9. Pancreatic walled off necrosis (WON): 2x5
   a) Epidemiology.
   b) Diagnosis of WON.
   c) Diagnosis of infection.
   

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   d) Indications for treatment.
   e) Endoscopic management.
10. Write the following with relation to benign liver tumours: 5+5
    a) Imaging of hepatic hemangioma.
    b) Clinical presentation and diagnosis of hepatic adenoma.

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