Download DNB 2016 Dec IMMUNO HEMATOLOGY AND TRANSFUSION MEDICINE PAPER 1 Question Paper

Download Diplomate of National Board (DNB) 2016 Dec IMMUNO HEMATOLOGY AND TRANSFUSION MEDICINE PAPER 1 Previous Question Paper

FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
POSSESSION / USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.

IMMUNO-HEMATOLOGY & TRANSFUSION MEDICINE

PAPER ? I
IHTM/D/16/15/I
Time : 3 hours
Max. Marks : 100

Important instructions:
? Attempt all questions in order.
? Each question carries 10 marks.
? Read the question carefully and answer to the point neatly and legibly.
? Do not leave any blank pages between two answers.
? Indicate the question number correctly for the answer in the margin space.
? Answer all the parts of a single question together.
? Start the answer to a question on a fresh page or leave adequate space between two answers.
? Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:



**********************
1. a) Prothrombin time ? Clinical utilities.
b) Explain International Normalized Ratio.

4+6
2. a) Coulter principle.
b) Optical platelet count.
c) Immature platelet fraction.

3+3+4
3. a) Graft versus host disease (GvHD).
b) Differentiate Transfusion from Transplant related GvHD
including management and prevention.

3+7
4. a) Define stem cells.
b) Hierarchy of Stem cells and iPS (induced Pluripotent Stem
cell).
c) Haematopoiesis from a pluripotent stem cell.

2+3+5
5. a) ADAMTS 13.
b) Thrombotic thrombocytopenic purpura.

4+6
6. a) Structure of Globin chain genes.
b) Haemoglobin synthesis.

5+5
7. Bleeding assessment tools.

10
8. a) Chromatography and Haemoglobin.
b) Hb Variant analysis.

5+5
9. a) Vitamin B12 metabolism.
b) Pernicious anemia.

5+5
10. a) ABO blood group system.
b) Molecular basis of A2 sub-group.
5+5
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