FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
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MEDICAL ONCOLOGY
PAPER - III
Time : 3 hours
Max. Marks : 100
Important instructions:
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- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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- Write short notes on:
Combined modality management of a 60 year old male with Stage III adenocarcinoma of lung:--- Content provided by FirstRanker.com ---
a) Factors deciding treatment plan. (1)
b) Concurrent chemoradiation dosages. (4)
c) Induction chemotherapy with radiation. (2)
d) Role of surgery in stage II NSCLC. (2)
e) Follow-up plan. (1) - PARP inhibitors: (3+2+2+3)
a) Principles and role of PARP in DNA repair.
b) Name PARP inhibitors.
c) Indications
d) Complications of their usage. - a) Define tumor microenvironment. (2)
b) How this information is now-being used in the treatment of chronic lymphocytic leukemia (CLL). (4)
c) Give briefly pharmacology of newer oral drugs being used in treatment of chronic lymphocytic leukemia. (4) - Cyberknife: (5+3+2)
a) Principles--- Content provided by FirstRanker.com ---
b) Indications
c) Limitations/complications - Hospice care: (1+3+3+3)
a) Definition.
b) Elements of Hospice care.--- Content provided by FirstRanker.com ---
c) Counseling strategies for patients and relatives.
d) Status of hospice care in India. - Out-patient management of febrile neutropenia : (2+2+2+2+2)
a) Assessment of risk of complications.
b) Antibiotic usage in an out-patient setting.--- Content provided by FirstRanker.com ---
c) Use of G-CSF — Regular vs PEG G-CSF.
d) Monitoring patient in an out-patient setting.
e) Indications for admission as in-patients. - Hormonal management of prostatic cancer: (4+2+4)
a) Various hormonal agents.--- Content provided by FirstRanker.com ---
b) Various screening methods for prostatic cancer.
c) Management of hormone resistant skeletal metastasis. - Cancers with viral etiology: (3+3+4)
a) List the viruses and related cancers.
b) Treatment of HCV infection.--- Content provided by FirstRanker.com ---
c) How will you confirm that the given tumour is due to viral infection? - Management of malignant pleural effusion/treatment of haemorrhagic pleural effusion/selection criteria for ICD: (2+4+2+2)
a) Lab investigations.
b) How to exclude inflammatory and other non-malignant causes of pleural effusion?
c) Selection of patients for ICD.--- Content provided by FirstRanker.com ---
d) Pleural cavity interventions. - Monoclonal Gammopathy of Undetermined Significance (MGUS): (2+2+3+3)
a) Definition.
b) Prognostic factors.
c) Initial treatment regimens and maintenance therapy.--- Content provided by FirstRanker.com ---
d) Allogenic BMT and treatment of relapsed disease.
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