Download VNSGU MBBS 2022 January 2nd Year Pharmacology Paper II MCQ Question Paper

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NC-2106000102020102-0

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Date of issue :

Sup. Sign. :

Centre :

Seat No.:

NC-2106000102020102-0

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Second Year M. B. B. S. Examination

January 2022

Pharmacology: Paper-II

(New Curriculum)

Time: 3 Hours]

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[Total Marks : 100

Instructions :

(1) ? ? ? ? ? ? ? ?.

Fillup strictly the details of signs on your answer book.

Name of the Examination: Second Year M. B. B. S.

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Name of the Subject: Pharmacology: Paper-II

Subject Code No.:

Seat No.: 2106000102020102

Section No. (1, 2,.....): Nil

Student's Signature

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(2) All MCQs are compulsory.

(3) Encircle the most appropriate correct option [i.e. (a), (b), (c) or (d)]

Multiple choice Questions (MCQs):

1. A 27-year-old female presented to OPD of infertility clinic. She was prescribed bromocriptine. What could be the possible reason?
   1. Hypelprorectinemia
   2. Polycystic ovarian disease

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   3. Hypogonadotropic hypogonadism
   4. Pelvic inflammatory disease
2. Fastest acting antityroid drug is:
   1. Potassium iodide
   2. Propylthiouracil

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   3. Carbimazole
   4. Cholestyramine
3. What is NOT TRUE about Anticoagulant drug ?
   1. Heparin is used by IV/SC route in Deep Vein Thrombosis
   2. aPTT monitoring is not required with low molecular weight heparin

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   3. Heparin can be used by IM route in Myocardial infarction
   4. Heparin is safe to use in pregnancy
4. Although incidence of lactic acidosis with metformin therapy is very less. All are risk factors for increased lactic acidosis in patient on metformin therapy EXCEPT:
   1. Advance age
   2. Liver dysfunction

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   3. Renal dysfunction
   4. Smoking
5. Drug of choice for acute adrenal insufficiency is:
   1. Oral prednisone
   2. IV hydrocortisone

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   3. IV betamethasone
   4. IV dexamethasone
6. Vitamin beneficial in osteoporosis in combination with vitamin D is:
   1. Vitamine E
   2. Vitamine A

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   3. Vitamine K
   4. Vitamine B
7. What is CORRECT about Hypolipidemic drug?
   1. Nicotinic acid is most effective in increasing level of HDL.
   2. Statins are most effective in reducing level of LDL.

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   3. Fibrates are most effective in reducing level of TG.
   4. All of the above.
8. Acetazolamide is indicated in
   1. Glaucoma
   2. Acute mountain sickness

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   3. For Alkaline diuresis
   4. All of the above.
9. Failure of oral contraceptive occur when used with any of these EXCEPT:
   1. Aspirin
   2. Tetracycline

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   3. Phenytoin
   4. Rifampicin
10. Sucralfate should not be administered with antacids, reason is
    1. Antacids increases sucralfate's systemic absorption
    2. Severe side effects are seen by combining these two drugs

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    3. Antacids decrease gastric, PH and makes sucralfate ineffective
    4. Sucralfate makes antacids ineffective by increasing acid secretion
11. Despite their short half life (2hrs) proton pump inhibitors cause prolonged suppression of acid secretion up to 48hrs because They-
    1. are Prodrug and undergo activation gradually
    2. exit from plasma & enter acid secretory canaliculi and stay there blocking acid secretion

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    3. are irreversible inhibitor of proton pump molecule
    4. are available as enteric coated capsules, from which gradually released
12. Which of the following aminoglycoside is used for topical purpose
    1. Kanamycin
    2. Neomycin

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    3. Amikacin
    4. All of the above
13. Following drugs are used in the treatment of Chloroquine resistant malaria concurrently with Arternisinins. EXCEPT
    1. Lumefentrine
    2. Quinine

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    3. Sulfadoxine + Pyrimethamine
    4. Mefloquine
14. Which of the following agent is used as sterilant?
    1. Chloroxylenol
    2. Chlorhexidine

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    3. Lysol
    4. Ethylene oxide
15. Following is INCORRECT about Metronidazole.
    1. It is highly effective in asymptomatic cyst passers of E.histolytica infection.
    2. It can causes disulfiram like reaction if used with alcohol.

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    3. It can be used in Anaerobic bacterial infection.
    4. It can be used in triple drug therapy for H. Pylori infection.
16. This of the following is NOT TRUE regarding Anti fungal drug.
    1. Fluconazole has achieved good concentration in CSF so can be used in fungal meningitis.
    2. Ketoconazole can produce gynecomastia in males.

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    3. Nystatin can be used as oral tablet in vaginal candidiasis infection.
    4. Amphotericin-B can produce nephrotoxicity.
17. Tirofiban is:
    1. Monoclonal antibodies
    2. Antiplatelet drugs

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    3. Anti-inflammatory drug
    4. Antianginal drug
18. In post MI patient which dose of aspirin is recommended?
    1. 20-50 mg/day
    2. 75 - 150 mg/day

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    3. 500-1000 mg/day
    4. 3000 - 4000 mg/day
19. What is NOT TRUE about Anticoagulant drug
    1. Heparin is used by IV/SC route in Deep Vein Thrombosis
    2. a PTT monitoring is not required with low molecular weight heparin

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    3. Heparin can be used by IM route in Myocardial infarction
    4. Heparin is safe to use in pregnancy
20. Praziquantel, an anthelmintic drug can be used in nursing mothers and pregnant women.
    1. True
    2. False

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