Download VNSGU MBBS 2nd Year 2015 December Pharmacology Paper II Question Paper

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M-4012-N

Second M. B. B. S. Examination

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December - 2015

Pharmacology: Paper - II

Time : 2 Hours]

[Total Marks : 40

Instructions:

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Fill up strictly the details of signs on your answer book.

Name of the Examination:

SECOND M. B. B. S.

Name of the Subject:

PHARMACOLOGY : PAPER - 2

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Subject Code No.: 4 0 1 2 Section No. (1,2....) Nil

(2) Answers must be brief, precise and to the point.

(3) Always give suitable examples and draw figures where necessary.

1. Answer very briefly: 9
   1. What is hyperbaric solution of lignocaine? What is the utility of such preparation?
   2. Name two drugs which can be used for medical closure of patent ductus arteriosus.

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   3. Give two advantages of non-benzodiazepines over diazepam as hypnotic drug.
   4. Name two drugs used in the treatment of leptospirosis.
   5. Mention two general anaesthetic agents preferred for paediatric patients?
   6. What is the limitation of naloxone while given in morphine poisoning? What is the way to prevent it?
   7. Name four antimicrobial agents used to treat anaerobic infection.

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   8. Name two indications of steroids in tuberculosis.
   9. Mention two reasons for not preferring ergometrine for induction of labour.
2. Answer any three: 9
   1. Enumerate various oral hypoglycemic drugs from different categories. Describe the mechanism of action and adverse effects of sulfonylureas.
   2. Write a short note on ACT.

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   3. Enumerate various agents used in gout. Describe mechanism of action and adverse effect of uricosuric agents.
   4. Enlist the advantages and disadvantages of atypical neuroleptics.

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3. Answer any four: 12
   1. Enumerate various AMAs to treat gram +ve infection. Describe the mechanism of action and enlist the adverse effects of penicillin.
   2. Describe the treatment of methyl alcohol poisoning.
   3. Describe the pharmacological basis for the use of oestrogen-progesterone combination as oral contraceptive pills and mention its adverse effects.
   4. Describe in relation with parkinson's disease: (1) on-off phenomenon (2) levodopa-carbidopa combination

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   5. Explain the pharmacological basis of use of (i) morphine in acute LVF (ii) methadone in morphine deaddiction
4. Answer any two: 10
   1. What is MDR-TB? Write down the general principles of treatment of MDR-TB and standardized RNTCP regimen for the same. Write the mechanism of action, adverse effects and uses of rifampin.
   2. Enumerate various drugs acting on glucocorticoid receptor. Describe the adverse effects and uses of the same with proper pharmacological basis.
   3. Classify general anaesthetic agents. Discuss critically about various factors affecting depth of anaesthesia. Your answer should include both inhalational and intravenous GA.

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M-4012-N]

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