M-4011
Second M. B. B. S. Examination
June/July – 2015
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Pharmacology: Paper - I Time: [Hours] [Total Marks: 40
Instructions:
(1) Fill up strictly the details of signs on your answer book.
Name of the Examination:
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SECOND M.B.B.S.Name of the Subject:
PHARMACOLOGY: PAPER - I
Subject Code No.: 4 0 1 1 Section No. (1,2....) Nil Student's Signature
(2) Answer must be precise, brief and to the point.
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(3) Always give suitable examples.- Answer very briefly. 9
- What is Prototype drug ?
- Define steady state concentration of a drug.
- Why mannitol is not given in pulmonary edema ?
- Mention two advantages of inhalation route of administration of a drug.
- Mention one difference between atropine and tropicamide.
- Why iron and folic acid are prescribed in pregnancy even when Lady is not anaemic ?
- Define tolerance.
- Why codeine is not recommended for symptomatic treatment of productive cough?
- Why administration of enalapril and spironolactone is not recommended simultaneously?
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M-4011] 1 [Contd...
- Answer any three: 9
- Enumerate various drugs from different categories for bronchial asthma. Describe their mode of administration.
- Enumerate various anticoagulants. Describe briefly the side effects/precautions when anticoagulants are used.
- Define therapeutic index. Explain briefly and with the help of diagram this concept.
- Describe briefly the significance of plasma protein binding.
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- Answer any four. 12
- Enumerate various statins. Describe briefly the mechanism of action; therapeutic uses and side effects of the same.
- Describe with examples the concept of first order and zero order kinetic of metabolism.
- Enumerate various ferrous salts with their respective percentage of elemental iron. Describe the status of SRP of iron in therapeutics.
- Enumerate various anti- diarrhoeal drugs from different categories. Describe mechanism of action and therapeutic uses of one of them.
- Describe with examples the concept of fixed-dose drug combination.
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- Answer any two. 10
- Classify parasympathomimetic drugs. Describe various therapeutic uses of these drugs.
- Enumerate various sympathomimetic drugs. Describe the therapeutic uses of the same.
- Enumerate various drugs from different categories for angina. Describe briefly the mechanism of action of nitrates for classical angina (Avoid the molecular mechanism.)
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M-4011] 2 [200]
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