Download VNSGU MBBS 2nd Year 2016 December Pharmacology Paper I Question Paper

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ER-4011

Second Year M. B. B. S. Examination

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December - 2016

Pharmacology : Paper - I

Time: 2 Hours] [Total Marks: 40

Instructions :

1. Fill up strictly the details of signs or your answer book.

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2. Answer must be brief, precise and to the point.
3. Always give suitable examples and draw figures where necessary.

SECTION - I

1. Answer very briefly: 10
   1. Explain the phenomenon of redistribution using a suitable example.
   2. State the toxicities of propantheline and dicyclomine.

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   3. Mention two types of receptor antagonism with one example for each.
   4. Give two examples of skeletal muscle relaxants. Give two indications of their use.
   5. Name two drugs each obtained from plant and animal source respectively and one therapeutic use of each drug.
   6. Enumerate two advantages and two disadvantages of intramuscular route of drug administration.

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[ER-4011] 1 [Contd...]

2. 1. Enumerate the indications of therapeutic drug monitoring.
   2. Why subcutaneous route of adrenaline is not preferred in anaphylactic shock? Which route is preferred?
   3. Explain iatrogenic disease giving suitable example.
   4. Give two examples of fixed dose combinations that you consider rational. Give justification for any one.

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2. Answer any four: 8
   1. Describe briefly with examples: (1) Therapeutic Window Phenomenon (2) Tachyphylaxis.
   2. Compare and contrast: Dopamine and Dobutamine.
   3. Write in short the pharmacological basis for the use of prostaglandin analogues in glaucoma.
   4. Enumerate therapeutic uses and adverse effects of ß Blockers.

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   5. Write in short on nasal decongestants.

SECTION - II

3. Answer any four: 12
   1. Describe in short therapeutic uses, adverse effects and mechanism of action of warfarin.
   2. Define pam Describe mechanism of action and adverse effects of metoclopramide.

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   3. Compare and contrast: Heparin and Low Molecular Weight Heparins.
   4. Justify the use of omeprazole in peptic ulcer, mentioning details of administration and important adverse effects.
   5. Write pharmacotherapy of acute bronchial asthma.

[ER-4011] 2 [Contd...]

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4. Answer any two: 10
   1. Describe briefly, therapeutic uses and adverse effects of digitalis.
   2. Classify diuretics. Describe the adverse effect profile of diuretics.
   3. Describe ACE Inhibitors.

[ER-4011] 3 [ 500 ]

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