Download VNSGU MBBS 2nd Year 2016 July Pharmacology Paper II Question Paper

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DZ-4012

Second Year M.B.B.S. Examination

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June / July - 2016

Pharmacology : Paper-II

Time : 2 Hours]

[Total Marks: 40

Instructions :

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1. Answers must be brief, precise and to the point.
2. Always give suitable examples and draw figures where necessary.

1. Answer very briefly: 9

   1. Name two pure µ opioid receptor antagonists.
   2. Which ß blocker is contraindicated in migraine prophylaxis?

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   3. Name two uses of neomycin with different routes of administration.
   4. Name four drugs used in MRSA.
   5. Give two reasons for using propranolol in thyrotoxicosis.
   6. Mention two agents used for operation theatre sterilization.
   7. Enumerate the names of four tocolytics and their clinical uses

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   8. Name two phosphodiesterase inhibitors with one use of each.
   9. Mention two agents used for mass prophylaxis to prevent filariasis.

2. Answer any three: 9

   1. Enlist various sedatives and hypnotics from different categories. Give comparative aspects of benzodiazepines and barbiturates pointwise.

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   2. Describe briefly the pharmacological basis of corticosteroids as anti-inflammatory and antiallergic. Enumerate the adverse effects and contraindications of glucocorticoids.
   3. Enumerate various NSAIDs. Write the uses of aspirin with pharmacological basis.
   4. What is recrudescence in relation with malaria?Write drug therapy for severe and complicated P. Falciparum Malaria.

3. Answer any four : 12

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   1. Describe briefly therapeutic uses and adverse effects of oral contraceptive pills.
   2. Write a short note on second generation fluoroquinolones
   3. Discuss critically about various factors affecting depth of anaesthesia.
   4. What is DOTS-plus programme? Write about various treatment regimens and strategies used under DOTS-plus guidelines.
   5. Pharmacotherapy of swine flu.

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4. Answer any two of the following : 10

   1. Enumerate various insulin preparations. Write in detail about newer insulin preparations, their uses and pros and cons of each.
   2. Classify antirheumatoid drugs. Describe mechanism of action and adverse effects of DMARDs (Disease modifying antirheumatic drugs).
   3. Classify antiparkinsonian drugs. Describe mechanism of action, pharmacokinetics, adverse effects and interactions of levodopa.

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DZ-4012]

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