Download VNSGU MBBS 2nd Year 2017 December Pharmacology Paper II Question Paper

BB-3715

Second Year M. B. B. S. Examination

November / December - 2017

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Pharmacology : Paper - II

Time : 2 Hours]

[Total Marks: 40

Instructions :

1. Fill up strictly the details of signs on your answer book.

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2. Answers must be brief, precise and to the point.
3. Always give suitable examples and draw figures where necessary.

SECTION I

1. Answer the following: (10)
   1. Name two drugs from third generation cephalosporines.
   2. Drug(s) used in the therapy of pulmonary arterial hypertension (PAH).

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   3. Name the drug related with dissociative anaesthesia.
   4. Give reasons for combination of imipenem with cilastin.
   5. Name the first member of a new class of synthetic tetracycline analogue.
   6. Names of two topical antifungal agents.
   7. Name the drug other than ethanol in treatment of methanol poisoning.

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   8. Explain the difference between recrudescence and relapse in a patient suffering from malaria.
   9. Name the antidote used to treat benzodiazepine overdose.
   10. Name the antimicrobial agent (AMA) contraindicated with neuromuscular blocker.

SECTION II

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2. Answer any four of the following: (8)
   1. Write a short note on emergency contraceptive agent ulipristal.
   2. Post exposure prophylaxis of HIV infection.
   3. Write a note on clavulanic acid.
   4. Write a note on levodopa-carbidopa combination.
   5. Enumerate the uses of clomiphene citrate.

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3. Answer any four of the following: (12)
   1. Write a short note on Selective Serotonin Reuptake Inhibitors (SSRIs).
   2. Explain various reactions to insulin therapy and their management.
   3. Describe additive, supra-additive & antagonistic combinations of antimicrobials with suitable examples.
   4. Describe the mechanism of action, advantages and disadvantages of radioactive iodine.

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   5. Discuss the mechanism of action, adverse effects and uses of rifampin.
4. Answer any two of the following: (10)
   1. Classify various drugs acting on opioid receptors. Describe the therapeutic uses, adverse effects and precautions/contraindications of the prototype drug morphine.
   2. Name the different classes of drugs available for treatment of epilepsy. Describe the mechanism of action, uses and adverse effects of any two drugs from different class.
   3. Classify Nonsteroidal Anti-inflammatory Drugs (NSAID). Describe the indications, adverse effects and contraindications of Aspirin.

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