Download VNSGU MBBS 2nd Year 2018 December Pharmacology Paper I Question Paper

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RK-3714

Second Year M. B. B. S. Examination

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November / December - 2018

Pharmacology : Paper - I

Time: 2 Hours]

[Total Marks: 40

Instructions:

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Fill up strictly the details of signs on your answer book.

Name of the Examination:

S. Y. M. B. B. S.

Name of the Subject:

PHARMACOLOGY PAPER - 1

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Subject Code No.: 3 7 1 4 Section No. (1, 2) NIL Student's Signature

1. Answers must be brief, precise and to the point.

2. Always give suitable examples & draw figures where necessary.

Section - I

1. Answer the following:
   1. What is clearance ?

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   2. Define pro-drug with an example.
   3. Explain mechanism of action of reserpine.
   4. What is first dose phenomenon ?
   5. Mention two advantages of fondaparinux over heparin.
   6. Name four newer drug delivery system.

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   7. How knowledge of plasma half-life of a drug can be helpful in therapeutics?
   8. What is an "orphan drug"?
   9. Give two examples of drug with very high therapeutic index.
   10. Write two uses of acetazolamide.

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2. Answer any four of the following:
   1. Explain potency with the help of diagram.
   2. What is PSVT? Mention its drug treatment.

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2. Answer any four of the following:
   1. Outline pharmacotherapy for motion sickness.

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   2. How sublingual administration of nitroglycerine brings about relief in acute angina pectoris? Also explain its mechanism of action.
   3. Discuss mechanism of action and side effect of metoclopramide.

Section - II

3. Answer any four of the following:
   1. Write short note on myasthenia gravis.

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   2. Classify beta-blockers. Enumerate their therapeutic uses and contraindications.
   3. Write mechanism of action, uses and advantages of proton pump inhibitors.
   4. Enumerate various factors affecting action of a drug. Explain any two.
   5. Explain any three uses of atropine giving pharmacological basis in detail.

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4. Answer any two of the following:
   1. Classify various adrenergic agents. Describe in detail management of cardiogenic shock.
   2. Classify drugs used for bronchial asthma. Write mechanism of action and adverse effects of bronchodilators.
   3. Compare and contrast fibrinolytics Vs antiplatelet drugs.

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