RK-3715
Second Year M. B. B. S. Examination
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November / December - 2018
Pharmacology: Paper - II
Time: 2 Hours] [Total Marks: 40
Instructions:
- Fill up strictly the details of signs on your answer book.
- Answers must be brief, precise and to the point.
- Always give suitable examples & draw figures where necessary.
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Section - I
- Answer the following: 10
- Mention four uses of morphine.
- Why sometime adrenalin is used with local anaesthesia ?
- Name two antibiotics which can be safely used in hepatic failure.
- What is diffusion hypoxia in relation to anaesthetic agent?
- Give two reasons for failure of chemotherapy.
- Why trimethoprim is combined with sulphamethoxazole?
- Name four drugs useful in treatment of cancer.
- What is an antiseptic agent? Give an example.
- Why oxytocin but not ergotamine is used for induction of labour?
- Name two important drugs for acne vulgaris.
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- Answer any four of the following: 8
- Mention in brief treatment of uncomplicated P. falciparum malaria.
- Write a short note on levodopa-carbidopa combination.
- Enumerate drugs useful in rheumatoid arthritis. Describe two disease modifying drugs.
- Classify antipsychotic agents. Mention various advantages of atypical antipsychotics.
- Write a note on d-tubocurarine.
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Section - II
- Answer any four of the following: 12
- Discuss drug therapy for upper respiratory tract infection.
- Enumerate aminoglycosides. Write their mechanism of action & therapeutic uses.
- What is somogyi effect? Explain mechanism of action and advantages of repaglinide.
- Write a short note on propylthiouracil.
- Discuss reasons for failure of chemotherapy.
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- Answer any two of the following: 10
- Classify steroids. Describe their uses according to duration of treatment.
- Classify antiretroviral drugs. Write guidelines for highly active antiretroviral therapy.
- Enumerate various insulin preparations. Outline therapy for coma due to diabetic ketoacidosis.
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