R-3715
Second Year M. B. B. S. Examination
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June / July 2018
Pharmacology : Paper - II
Time : 2 Hours] | [Total Marks: 40 |
Instructions :
- Fill up strictly the details of signs on your answer book.
- Answers must be brief, precise and to the point.
- Always give suitable examples and draw figures where necessary.
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SECTION - I
- Answer the following in brief: (10)
- Morphine is contraindicated in patients with head injury. Give reasons.
- Write two uses of chloroquine apart from malaria.
- Name two drugs used in the treatment of HIV infection.
- Explain the uricosuric action of probenecid.
- Name the new anti-tuberculous drug approved in India for National Tuberculosis Programme.
- Name two beta-lactame inhibitors.
- Name the drug used specifically as urinary analgesic.
- Monitoring of plasma concentration of phenytoin is useful in minimizing its toxicity. (Give your answer in relation to pharmacokinetics).
- Name two drugs used in treatment of amoebic liver abscess.
- Write two drugs of different class for migraine prophylaxis.
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[ Contd.....
- Answer any four of the following: (8)
- Uses of iodine and iodides.
- Write a short note on emergency contraceptive agent.
- Write a note on sulbactam.
- Discuss briefly the importance of three different doses of aspirin in therapeutics.
- Describe the advantages and disadvantages of combination of LA (lidocaine) with a vasoconstrictor (adrenaline).
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SECTION - II
- Answer any four of the following: (12)
- Classify the newer non-benzodiazepine hypnotics. Describe their advantages over the older ones?
- Describe briefly the mechanism of action and uses of Albendazole.
- Enlist drugs for Parkinson's disease. Mention mechanism of action and adverse drug reactions of any one of the anti-parkinsonian agents.
- Write a short note on the pharmacotherapy of type I and type II lepra reactions.
- Discuss the pharmacotherapy of Disease Modifying Anti-Rheumatic Drugs (DMARD).
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- Answer any two of the following: (10)
- Write the classification of corticosteroids. Discuss the Pharmacological actions and adverse effects of glucocorticoids.
- Describe the pharmacotherapy of type I diabetes mellitus. Discuss the various insulin analogues in detail.
- Enumerate the five commonly used drugs for tonic-clonic seizures. Describe in brief their mechanism of action and adverse effects.
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[100]
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